Consistent and chronic cochlear implant use partially reverses cortical effects of single sided deafness in children

Abstract Potentially neuroprotective effects of CI use were studied in 22 children with single sided deafness (SSD). Auditory-evoked EEG confirmed strengthened representation of the intact ear in the ipsilateral auditory cortex at initial CI activation in children with early-onset SSD (n = 15) and l...

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Autores principales:	Hyo-Jeong Lee, Daniel Smieja, Melissa Jane Polonenko, Sharon Lynn Cushing, Blake Croll Papsin, Karen Ann Gordon
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/7475061b15f94555875f14d24ed7f01f
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spelling	oai:doaj.org-article:7475061b15f94555875f14d24ed7f01f2021-12-02T16:18:02ZConsistent and chronic cochlear implant use partially reverses cortical effects of single sided deafness in children10.1038/s41598-020-78371-62045-2322https://doaj.org/article/7475061b15f94555875f14d24ed7f01f2020-12-01T00:00:00Zhttps://doi.org/10.1038/s41598-020-78371-6https://doaj.org/toc/2045-2322Abstract Potentially neuroprotective effects of CI use were studied in 22 children with single sided deafness (SSD). Auditory-evoked EEG confirmed strengthened representation of the intact ear in the ipsilateral auditory cortex at initial CI activation in children with early-onset SSD (n = 15) and late-onset SSD occurring suddenly in later childhood/adolescence (n = 7). In early-onset SSD, representation of the hearing ear decreased with chronic CI experience and expected lateralization to the contralateral auditory cortex from the CI increased with longer daily CI use. In late-onset SSD, abnormally high activity from the intact ear in the ipsilateral cortex reduced, but responses from the deaf ear weakened despite CI use. Results suggest that: (1) cortical reorganization driven by unilateral hearing can occur throughout childhood; (2) chronic and consistent CI use can partially reverse these effects; and (3) CI use may not protect children with late-onset SSD from ongoing deterioration of pathways from the deaf ear.Hyo-Jeong LeeDaniel SmiejaMelissa Jane PolonenkoSharon Lynn CushingBlake Croll PapsinKaren Ann GordonNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Hyo-Jeong Lee Daniel Smieja Melissa Jane Polonenko Sharon Lynn Cushing Blake Croll Papsin Karen Ann Gordon Consistent and chronic cochlear implant use partially reverses cortical effects of single sided deafness in children
description	Abstract Potentially neuroprotective effects of CI use were studied in 22 children with single sided deafness (SSD). Auditory-evoked EEG confirmed strengthened representation of the intact ear in the ipsilateral auditory cortex at initial CI activation in children with early-onset SSD (n = 15) and late-onset SSD occurring suddenly in later childhood/adolescence (n = 7). In early-onset SSD, representation of the hearing ear decreased with chronic CI experience and expected lateralization to the contralateral auditory cortex from the CI increased with longer daily CI use. In late-onset SSD, abnormally high activity from the intact ear in the ipsilateral cortex reduced, but responses from the deaf ear weakened despite CI use. Results suggest that: (1) cortical reorganization driven by unilateral hearing can occur throughout childhood; (2) chronic and consistent CI use can partially reverse these effects; and (3) CI use may not protect children with late-onset SSD from ongoing deterioration of pathways from the deaf ear.
format	article
author	Hyo-Jeong Lee Daniel Smieja Melissa Jane Polonenko Sharon Lynn Cushing Blake Croll Papsin Karen Ann Gordon
author_facet	Hyo-Jeong Lee Daniel Smieja Melissa Jane Polonenko Sharon Lynn Cushing Blake Croll Papsin Karen Ann Gordon
author_sort	Hyo-Jeong Lee
title	Consistent and chronic cochlear implant use partially reverses cortical effects of single sided deafness in children
title_short	Consistent and chronic cochlear implant use partially reverses cortical effects of single sided deafness in children
title_full	Consistent and chronic cochlear implant use partially reverses cortical effects of single sided deafness in children
title_fullStr	Consistent and chronic cochlear implant use partially reverses cortical effects of single sided deafness in children
title_full_unstemmed	Consistent and chronic cochlear implant use partially reverses cortical effects of single sided deafness in children
title_sort	consistent and chronic cochlear implant use partially reverses cortical effects of single sided deafness in children
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/7475061b15f94555875f14d24ed7f01f
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Consistent and chronic cochlear implant use partially reverses cortical effects of single sided deafness in children

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