Identification of a pocket factor that is critical to Zika virus assembly

Here, the authors provide a 3.4 Å resolution structure of mature Zika virus (ZIKV) and identify two lipid moieties, coordinated by hydrophobic residues of the M and E transmembrane helices and between two helices of E protein, that play an essential role in the ZIKV assembly pathway.

Guardado en:

Detalles Bibliográficos
Autores principales:	Nadia M. DiNunno, Daniel J. Goetschius, Anoop Narayanan, Sydney A. Majowicz, Ibrahim Moustafa, Carol M. Bator, Susan L. Hafenstein, Joyce Jose
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/7496445a4f9c45ed87e234236a9b0144
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:7496445a4f9c45ed87e234236a9b0144
record_format	dspace
spelling	oai:doaj.org-article:7496445a4f9c45ed87e234236a9b01442021-12-02T17:18:25ZIdentification of a pocket factor that is critical to Zika virus assembly10.1038/s41467-020-18747-42041-1723https://doaj.org/article/7496445a4f9c45ed87e234236a9b01442020-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-18747-4https://doaj.org/toc/2041-1723Here, the authors provide a 3.4 Å resolution structure of mature Zika virus (ZIKV) and identify two lipid moieties, coordinated by hydrophobic residues of the M and E transmembrane helices and between two helices of E protein, that play an essential role in the ZIKV assembly pathway.Nadia M. DiNunnoDaniel J. GoetschiusAnoop NarayananSydney A. MajowiczIbrahim MoustafaCarol M. BatorSusan L. HafensteinJoyce JoseNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-8 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Nadia M. DiNunno Daniel J. Goetschius Anoop Narayanan Sydney A. Majowicz Ibrahim Moustafa Carol M. Bator Susan L. Hafenstein Joyce Jose Identification of a pocket factor that is critical to Zika virus assembly
description	Here, the authors provide a 3.4 Å resolution structure of mature Zika virus (ZIKV) and identify two lipid moieties, coordinated by hydrophobic residues of the M and E transmembrane helices and between two helices of E protein, that play an essential role in the ZIKV assembly pathway.
format	article
author	Nadia M. DiNunno Daniel J. Goetschius Anoop Narayanan Sydney A. Majowicz Ibrahim Moustafa Carol M. Bator Susan L. Hafenstein Joyce Jose
author_facet	Nadia M. DiNunno Daniel J. Goetschius Anoop Narayanan Sydney A. Majowicz Ibrahim Moustafa Carol M. Bator Susan L. Hafenstein Joyce Jose
author_sort	Nadia M. DiNunno
title	Identification of a pocket factor that is critical to Zika virus assembly
title_short	Identification of a pocket factor that is critical to Zika virus assembly
title_full	Identification of a pocket factor that is critical to Zika virus assembly
title_fullStr	Identification of a pocket factor that is critical to Zika virus assembly
title_full_unstemmed	Identification of a pocket factor that is critical to Zika virus assembly
title_sort	identification of a pocket factor that is critical to zika virus assembly
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/7496445a4f9c45ed87e234236a9b0144
work_keys_str_mv	AT nadiamdinunno identificationofapocketfactorthatiscriticaltozikavirusassembly AT danieljgoetschius identificationofapocketfactorthatiscriticaltozikavirusassembly AT anoopnarayanan identificationofapocketfactorthatiscriticaltozikavirusassembly AT sydneyamajowicz identificationofapocketfactorthatiscriticaltozikavirusassembly AT ibrahimmoustafa identificationofapocketfactorthatiscriticaltozikavirusassembly AT carolmbator identificationofapocketfactorthatiscriticaltozikavirusassembly AT susanlhafenstein identificationofapocketfactorthatiscriticaltozikavirusassembly AT joycejose identificationofapocketfactorthatiscriticaltozikavirusassembly
_version_	1718381093577555968

Identification of a pocket factor that is critical to Zika virus assembly

Ejemplares similares