Insights into the Middle Eastern paternal genetic pool in Tunisia: high prevalence of T-M70 haplogroup in an Arab population

Abstract To obtain refreshed insights into the paternal lineages of Tunisian populations, Y-chromosome diversity was assessed in two populations belonging to an Arab genealogical lineage, Kairouan and Wesletia, as well as in four Tunisian Andalusian populations, Testour, Slouguia, Qalaat-El-Andalous...

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Autores principales:	Sarra Elkamel, Sofia L. Marques, Luis Alvarez, Veronica Gomes, Sami Boussetta, Soufia Mourali-Chebil, Houssein Khodjet-El-Khil, Lotfi Cherni, Amel Benammar-Elgaaied, Maria J. Prata
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/749e912f28314418ba7aa6763a6b8601
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spelling	oai:doaj.org-article:749e912f28314418ba7aa6763a6b86012021-12-02T17:06:10ZInsights into the Middle Eastern paternal genetic pool in Tunisia: high prevalence of T-M70 haplogroup in an Arab population10.1038/s41598-021-95144-x2045-2322https://doaj.org/article/749e912f28314418ba7aa6763a6b86012021-08-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-95144-xhttps://doaj.org/toc/2045-2322Abstract To obtain refreshed insights into the paternal lineages of Tunisian populations, Y-chromosome diversity was assessed in two populations belonging to an Arab genealogical lineage, Kairouan and Wesletia, as well as in four Tunisian Andalusian populations, Testour, Slouguia, Qalaat-El-Andalous and El Alia. The Arabs from Kairouan revealed 73.47% of E-M81 and close affinities with Berber groups, indicating they are likely arabized Berbers, clearly differentiated from the Arabs from Wesletia, who harbored the highest frequency (71.8%) of the Middle Eastern component ever observed in North Africa. In the Tunisian Andalusians, the North African component largely prevailed, followed by the Middle Eastern contribution. Global comparative analysis highlighted the heterogeneity of Tunisian populations, among which, as a whole, dominated a set of lineages ascribed to be of autochthonous Berber origin (71.67%), beside a component of essentially Middle Eastern extraction (18.35%), and signatures of Sub-Saharan (5.2%), European (3.45%) and Asiatic (1.33%) contributions. The remarkable frequency of T-M70 in Wesletia (17.4%) prompted to refine its phylogeographic analysis, allowing to confirm its Middle Eastern origin, though signs of local evolution in Northern Africa were also detected. Evidence was clear on the ancient introduction of T lineages into the region, probably since Neolithic times associated to spread of agriculture.Sarra ElkamelSofia L. MarquesLuis AlvarezVeronica GomesSami BoussettaSoufia Mourali-ChebilHoussein Khodjet-El-KhilLotfi CherniAmel Benammar-ElgaaiedMaria J. PrataNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Sarra Elkamel Sofia L. Marques Luis Alvarez Veronica Gomes Sami Boussetta Soufia Mourali-Chebil Houssein Khodjet-El-Khil Lotfi Cherni Amel Benammar-Elgaaied Maria J. Prata Insights into the Middle Eastern paternal genetic pool in Tunisia: high prevalence of T-M70 haplogroup in an Arab population
description	Abstract To obtain refreshed insights into the paternal lineages of Tunisian populations, Y-chromosome diversity was assessed in two populations belonging to an Arab genealogical lineage, Kairouan and Wesletia, as well as in four Tunisian Andalusian populations, Testour, Slouguia, Qalaat-El-Andalous and El Alia. The Arabs from Kairouan revealed 73.47% of E-M81 and close affinities with Berber groups, indicating they are likely arabized Berbers, clearly differentiated from the Arabs from Wesletia, who harbored the highest frequency (71.8%) of the Middle Eastern component ever observed in North Africa. In the Tunisian Andalusians, the North African component largely prevailed, followed by the Middle Eastern contribution. Global comparative analysis highlighted the heterogeneity of Tunisian populations, among which, as a whole, dominated a set of lineages ascribed to be of autochthonous Berber origin (71.67%), beside a component of essentially Middle Eastern extraction (18.35%), and signatures of Sub-Saharan (5.2%), European (3.45%) and Asiatic (1.33%) contributions. The remarkable frequency of T-M70 in Wesletia (17.4%) prompted to refine its phylogeographic analysis, allowing to confirm its Middle Eastern origin, though signs of local evolution in Northern Africa were also detected. Evidence was clear on the ancient introduction of T lineages into the region, probably since Neolithic times associated to spread of agriculture.
format	article
author	Sarra Elkamel Sofia L. Marques Luis Alvarez Veronica Gomes Sami Boussetta Soufia Mourali-Chebil Houssein Khodjet-El-Khil Lotfi Cherni Amel Benammar-Elgaaied Maria J. Prata
author_facet	Sarra Elkamel Sofia L. Marques Luis Alvarez Veronica Gomes Sami Boussetta Soufia Mourali-Chebil Houssein Khodjet-El-Khil Lotfi Cherni Amel Benammar-Elgaaied Maria J. Prata
author_sort	Sarra Elkamel
title	Insights into the Middle Eastern paternal genetic pool in Tunisia: high prevalence of T-M70 haplogroup in an Arab population
title_short	Insights into the Middle Eastern paternal genetic pool in Tunisia: high prevalence of T-M70 haplogroup in an Arab population
title_full	Insights into the Middle Eastern paternal genetic pool in Tunisia: high prevalence of T-M70 haplogroup in an Arab population
title_fullStr	Insights into the Middle Eastern paternal genetic pool in Tunisia: high prevalence of T-M70 haplogroup in an Arab population
title_full_unstemmed	Insights into the Middle Eastern paternal genetic pool in Tunisia: high prevalence of T-M70 haplogroup in an Arab population
title_sort	insights into the middle eastern paternal genetic pool in tunisia: high prevalence of t-m70 haplogroup in an arab population
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/749e912f28314418ba7aa6763a6b8601
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Insights into the Middle Eastern paternal genetic pool in Tunisia: high prevalence of T-M70 haplogroup in an Arab population

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