The HIF target MAFF promotes tumor invasion and metastasis through IL11 and STAT3 signaling

Hypoxia plays a critical role in tumor progression including invasion and metastasis. Here, the authors screened several hypoxia inducible genes and identified the oncogenic role of MAFF in breast cancer metastasis and that it activates IL11/STAT3 pathway.

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Autores principales:	Eui Jung Moon, Stephano S. Mello, Caiyun G. Li, Jen-Tsan Chi, Kaushik Thakkar, Jacob G. Kirkland, Edward L. Lagory, Ik Jae Lee, Anh N. Diep, Yu Miao, Marjan Rafat, Marta Vilalta, Laura Castellini, Adam J. Krieg, Edward E. Graves, Laura D. Attardi, Amato J. Giaccia
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/74a0bdf041f848a69bf653962a2ec1b4
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

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spelling	oai:doaj.org-article:74a0bdf041f848a69bf653962a2ec1b42021-12-02T18:36:59ZThe HIF target MAFF promotes tumor invasion and metastasis through IL11 and STAT3 signaling10.1038/s41467-021-24631-62041-1723https://doaj.org/article/74a0bdf041f848a69bf653962a2ec1b42021-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-24631-6https://doaj.org/toc/2041-1723Hypoxia plays a critical role in tumor progression including invasion and metastasis. Here, the authors screened several hypoxia inducible genes and identified the oncogenic role of MAFF in breast cancer metastasis and that it activates IL11/STAT3 pathway.Eui Jung MoonStephano S. MelloCaiyun G. LiJen-Tsan ChiKaushik ThakkarJacob G. KirklandEdward L. LagoryIk Jae LeeAnh N. DiepYu MiaoMarjan RafatMarta VilaltaLaura CastelliniAdam J. KriegEdward E. GravesLaura D. AttardiAmato J. GiacciaNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Eui Jung Moon Stephano S. Mello Caiyun G. Li Jen-Tsan Chi Kaushik Thakkar Jacob G. Kirkland Edward L. Lagory Ik Jae Lee Anh N. Diep Yu Miao Marjan Rafat Marta Vilalta Laura Castellini Adam J. Krieg Edward E. Graves Laura D. Attardi Amato J. Giaccia The HIF target MAFF promotes tumor invasion and metastasis through IL11 and STAT3 signaling
description	Hypoxia plays a critical role in tumor progression including invasion and metastasis. Here, the authors screened several hypoxia inducible genes and identified the oncogenic role of MAFF in breast cancer metastasis and that it activates IL11/STAT3 pathway.
format	article
author	Eui Jung Moon Stephano S. Mello Caiyun G. Li Jen-Tsan Chi Kaushik Thakkar Jacob G. Kirkland Edward L. Lagory Ik Jae Lee Anh N. Diep Yu Miao Marjan Rafat Marta Vilalta Laura Castellini Adam J. Krieg Edward E. Graves Laura D. Attardi Amato J. Giaccia
author_facet	Eui Jung Moon Stephano S. Mello Caiyun G. Li Jen-Tsan Chi Kaushik Thakkar Jacob G. Kirkland Edward L. Lagory Ik Jae Lee Anh N. Diep Yu Miao Marjan Rafat Marta Vilalta Laura Castellini Adam J. Krieg Edward E. Graves Laura D. Attardi Amato J. Giaccia
author_sort	Eui Jung Moon
title	The HIF target MAFF promotes tumor invasion and metastasis through IL11 and STAT3 signaling
title_short	The HIF target MAFF promotes tumor invasion and metastasis through IL11 and STAT3 signaling
title_full	The HIF target MAFF promotes tumor invasion and metastasis through IL11 and STAT3 signaling
title_fullStr	The HIF target MAFF promotes tumor invasion and metastasis through IL11 and STAT3 signaling
title_full_unstemmed	The HIF target MAFF promotes tumor invasion and metastasis through IL11 and STAT3 signaling
title_sort	hif target maff promotes tumor invasion and metastasis through il11 and stat3 signaling
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/74a0bdf041f848a69bf653962a2ec1b4
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The HIF target MAFF promotes tumor invasion and metastasis through IL11 and STAT3 signaling

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