An optogenetic system to control membrane phospholipid asymmetry through flippase activation in budding yeast

Abstract Lipid asymmetry in biological membranes is essential for various cell functions, such as cell polarity, cytokinesis, and apoptosis. P4-ATPases (flippases) are involved in the generation of such asymmetry. In Saccharomyces cerevisiae, the protein kinases Fpk1p/Fpk2p activate the P4-ATPases D...

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Autores principales: Tomomi Suzuki, Tetsuo Mioka, Kazuma Tanaka, Akira Nagatani
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/74a8bd5f78ee4df692717e1bdefea086
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