An optogenetic system to control membrane phospholipid asymmetry through flippase activation in budding yeast

Abstract Lipid asymmetry in biological membranes is essential for various cell functions, such as cell polarity, cytokinesis, and apoptosis. P4-ATPases (flippases) are involved in the generation of such asymmetry. In Saccharomyces cerevisiae, the protein kinases Fpk1p/Fpk2p activate the P4-ATPases D...

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Bibliographic Details
Main Authors: Tomomi Suzuki, Tetsuo Mioka, Kazuma Tanaka, Akira Nagatani
Format: article
Language:EN
Published: Nature Portfolio 2020
Subjects:
R
Q
Online Access:https://doaj.org/article/74a8bd5f78ee4df692717e1bdefea086
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