Is there a relationship between the prevalence of autoimmune thyroid disease and diabetic kidney disease?

Autoimmune thyroid disease (AITD) is more common among diabetes mellitus (DM) patients and may impact its microvascular complications. The present study aimed to assess the relationship between AITD and the prevalence of diabetic kidney disease (DKD) in patients with diabetes mellitus type 1 (DM1)....

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Autores principales:	Stefanowicz-Rutkowska Magdalena Maria, Matuszewski Wojciech, Gontarz-Nowak Katarzyna, Bandurska-Stankiewicz Elżbieta Maria
Formato:	article
Lenguaje:	EN
Publicado:	De Gruyter 2021
Materias:	diabetes autoimmune thyroid disease diabetic kidney disease albuminuria Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/74b38afb87b04882988c84f7b66a1614
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spelling	oai:doaj.org-article:74b38afb87b04882988c84f7b66a16142021-12-05T14:10:41ZIs there a relationship between the prevalence of autoimmune thyroid disease and diabetic kidney disease?2391-541210.1515/biol-2021-0064https://doaj.org/article/74b38afb87b04882988c84f7b66a16142021-06-01T00:00:00Zhttps://doi.org/10.1515/biol-2021-0064https://doaj.org/toc/2391-5412Autoimmune thyroid disease (AITD) is more common among diabetes mellitus (DM) patients and may impact its microvascular complications. The present study aimed to assess the relationship between AITD and the prevalence of diabetic kidney disease (DKD) in patients with diabetes mellitus type 1 (DM1). Anthropometric parameters, parameters of metabolic control of DM, thyreometabolic status, and the UACR were assessed. DKD was diagnosed if patients’ UACR level was ≥30 mg/g or eGFR level was <60 mL/min. This study involved 144 patients with DM1 aged 36.2 ± 11.7 years: 49 men and 95 women. Significant differences in creatinine, eGFR, and UACR levels were found in patients with DKD. fT3 concentration was significantly lower among DKD patients. A significantly higher probability of DKD was found in DM1 patients with lower fT3 levels. Patients with DM1 and AITD had significantly lower creatinine levels than the control group. However, the study did not show any significant relationship between AITD and the occurrence of DKD in patients with DM1. Significantly lower fT3 concentrations in DKD patients may be caused by metabolic disorders in the course of DKD and require further cohort studies in a larger population of patients with DM1 and AITD.Stefanowicz-Rutkowska Magdalena MariaMatuszewski WojciechGontarz-Nowak KatarzynaBandurska-Stankiewicz Elżbieta MariaDe Gruyterarticlediabetesautoimmune thyroid diseasediabetic kidney diseasealbuminuriaBiology (General)QH301-705.5ENOpen Life Sciences, Vol 16, Iss 1, Pp 611-619 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	diabetes autoimmune thyroid disease diabetic kidney disease albuminuria Biology (General) QH301-705.5
spellingShingle	diabetes autoimmune thyroid disease diabetic kidney disease albuminuria Biology (General) QH301-705.5 Stefanowicz-Rutkowska Magdalena Maria Matuszewski Wojciech Gontarz-Nowak Katarzyna Bandurska-Stankiewicz Elżbieta Maria Is there a relationship between the prevalence of autoimmune thyroid disease and diabetic kidney disease?
description	Autoimmune thyroid disease (AITD) is more common among diabetes mellitus (DM) patients and may impact its microvascular complications. The present study aimed to assess the relationship between AITD and the prevalence of diabetic kidney disease (DKD) in patients with diabetes mellitus type 1 (DM1). Anthropometric parameters, parameters of metabolic control of DM, thyreometabolic status, and the UACR were assessed. DKD was diagnosed if patients’ UACR level was ≥30 mg/g or eGFR level was <60 mL/min. This study involved 144 patients with DM1 aged 36.2 ± 11.7 years: 49 men and 95 women. Significant differences in creatinine, eGFR, and UACR levels were found in patients with DKD. fT3 concentration was significantly lower among DKD patients. A significantly higher probability of DKD was found in DM1 patients with lower fT3 levels. Patients with DM1 and AITD had significantly lower creatinine levels than the control group. However, the study did not show any significant relationship between AITD and the occurrence of DKD in patients with DM1. Significantly lower fT3 concentrations in DKD patients may be caused by metabolic disorders in the course of DKD and require further cohort studies in a larger population of patients with DM1 and AITD.
format	article
author	Stefanowicz-Rutkowska Magdalena Maria Matuszewski Wojciech Gontarz-Nowak Katarzyna Bandurska-Stankiewicz Elżbieta Maria
author_facet	Stefanowicz-Rutkowska Magdalena Maria Matuszewski Wojciech Gontarz-Nowak Katarzyna Bandurska-Stankiewicz Elżbieta Maria
author_sort	Stefanowicz-Rutkowska Magdalena Maria
title	Is there a relationship between the prevalence of autoimmune thyroid disease and diabetic kidney disease?
title_short	Is there a relationship between the prevalence of autoimmune thyroid disease and diabetic kidney disease?
title_full	Is there a relationship between the prevalence of autoimmune thyroid disease and diabetic kidney disease?
title_fullStr	Is there a relationship between the prevalence of autoimmune thyroid disease and diabetic kidney disease?
title_full_unstemmed	Is there a relationship between the prevalence of autoimmune thyroid disease and diabetic kidney disease?
title_sort	is there a relationship between the prevalence of autoimmune thyroid disease and diabetic kidney disease?
publisher	De Gruyter
publishDate	2021
url	https://doaj.org/article/74b38afb87b04882988c84f7b66a1614
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Is there a relationship between the prevalence of autoimmune thyroid disease and diabetic kidney disease?

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