Targeting of apoptosis gene loci by reprogramming factors leads to selective eradication of leukemia cells
Yamanaka factors can reprogram somatic and cancer cells into induced pluripotent stem cells. Here, the authors show that the induction of these factors in acute myeloid leukemia leads to apoptosis of leukemia cells in vivo, and this is through modulation of chromatin accessibility to apoptotic genes...
Saved in:
| Main Authors: | , , , , , , , , , , , , , , |
|---|---|
| Format: | article |
| Language: | EN |
| Published: |
Nature Portfolio
2019
|
| Subjects: | |
| Online Access: | https://doaj.org/article/74b5e3075d964424ba332b6b527e4378 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|