Induction of anergic or regulatory tumor-specific CD4+ T cells in the tumor-draining lymph node

Induction of anergic or regulatory tumor-specific CD4+ T cells in the tumor-draining lymph node

Tumor neoantigens can be drained to the lymph nodes, but the nature and the significance of the induced immune responses are still unclear. Here the authors use a mouse genetic tumor model to show that tumor-specific CD4 T cells can become anergic or suppressive in the draining lymph node to modulat...

Full description

Saved in:
Bibliographic Details
Main Authors: Ruby Alonso, Héloïse Flament, Sébastien Lemoine, Christine Sedlik, Emanuel Bottasso, Isabel Péguillet, Virginie Prémel, Jordan Denizeau, Marion Salou, Aurélie Darbois, Nicolás Gonzalo Núñez, Benoit Salomon, David Gross, Eliane Piaggio, Olivier Lantz
Format: article
Language:EN
Published: Nature Portfolio 2018
Subjects:
Science
Q
Online Access:https://doaj.org/article/74b8aa3d1148474e8cae7856e61a4c79
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doaj.org/article/74b8aa3d1148474e8cae7856e61a4c79

Similar Items