Bioprinting Au Natural: The Biologics of Bioinks
The development of appropriate bioinks is a complex task, dependent on the mechanical and biochemical requirements of the final construct and the type of printer used for fabrication. The two most common tissue printers are micro-extrusion and digital light projection printers. Here we briefly discu...
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MDPI AG
2021
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oai:doaj.org-article:74c00ddd7e5f4be992c59002fb96c1752021-11-25T16:52:36ZBioprinting Au Natural: The Biologics of Bioinks10.3390/biom111115932218-273Xhttps://doaj.org/article/74c00ddd7e5f4be992c59002fb96c1752021-10-01T00:00:00Zhttps://www.mdpi.com/2218-273X/11/11/1593https://doaj.org/toc/2218-273XThe development of appropriate bioinks is a complex task, dependent on the mechanical and biochemical requirements of the final construct and the type of printer used for fabrication. The two most common tissue printers are micro-extrusion and digital light projection printers. Here we briefly discuss the required characteristics of a bioink for each of these printing processes. However, physical printing is only a short window in the lifespan of a printed construct—the system must support and facilitate cellular development after it is printed. To that end, we provide a broad overview of some of the biological molecules currently used as bioinks. Each molecule has advantages for specific tissues/cells, and potential disadvantages are discussed, along with examples of their current use in the field. Notably, it is stressed that active researchers are trending towards the use of composite bioinks. Utilizing the strengths from multiple materials is highlighted as a key component of bioink development.Kelsey WillsonAnthony AtalaJames J. YooMDPI AGarticlebioprintingbioink3D printingMicrobiologyQR1-502ENBiomolecules, Vol 11, Iss 1593, p 1593 (2021) |
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bioprinting bioink 3D printing Microbiology QR1-502 |
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bioprinting bioink 3D printing Microbiology QR1-502 Kelsey Willson Anthony Atala James J. Yoo Bioprinting Au Natural: The Biologics of Bioinks |
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The development of appropriate bioinks is a complex task, dependent on the mechanical and biochemical requirements of the final construct and the type of printer used for fabrication. The two most common tissue printers are micro-extrusion and digital light projection printers. Here we briefly discuss the required characteristics of a bioink for each of these printing processes. However, physical printing is only a short window in the lifespan of a printed construct—the system must support and facilitate cellular development after it is printed. To that end, we provide a broad overview of some of the biological molecules currently used as bioinks. Each molecule has advantages for specific tissues/cells, and potential disadvantages are discussed, along with examples of their current use in the field. Notably, it is stressed that active researchers are trending towards the use of composite bioinks. Utilizing the strengths from multiple materials is highlighted as a key component of bioink development. |
format |
article |
author |
Kelsey Willson Anthony Atala James J. Yoo |
author_facet |
Kelsey Willson Anthony Atala James J. Yoo |
author_sort |
Kelsey Willson |
title |
Bioprinting Au Natural: The Biologics of Bioinks |
title_short |
Bioprinting Au Natural: The Biologics of Bioinks |
title_full |
Bioprinting Au Natural: The Biologics of Bioinks |
title_fullStr |
Bioprinting Au Natural: The Biologics of Bioinks |
title_full_unstemmed |
Bioprinting Au Natural: The Biologics of Bioinks |
title_sort |
bioprinting au natural: the biologics of bioinks |
publisher |
MDPI AG |
publishDate |
2021 |
url |
https://doaj.org/article/74c00ddd7e5f4be992c59002fb96c175 |
work_keys_str_mv |
AT kelseywillson bioprintingaunaturalthebiologicsofbioinks AT anthonyatala bioprintingaunaturalthebiologicsofbioinks AT jamesjyoo bioprintingaunaturalthebiologicsofbioinks |
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1718412904142733312 |