Bioprinting Au Natural: The Biologics of Bioinks

The development of appropriate bioinks is a complex task, dependent on the mechanical and biochemical requirements of the final construct and the type of printer used for fabrication. The two most common tissue printers are micro-extrusion and digital light projection printers. Here we briefly discu...

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Autores principales: Kelsey Willson, Anthony Atala, James J. Yoo
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Lenguaje:EN
Publicado: MDPI AG 2021
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Acceso en línea:https://doaj.org/article/74c00ddd7e5f4be992c59002fb96c175
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spelling oai:doaj.org-article:74c00ddd7e5f4be992c59002fb96c1752021-11-25T16:52:36ZBioprinting Au Natural: The Biologics of Bioinks10.3390/biom111115932218-273Xhttps://doaj.org/article/74c00ddd7e5f4be992c59002fb96c1752021-10-01T00:00:00Zhttps://www.mdpi.com/2218-273X/11/11/1593https://doaj.org/toc/2218-273XThe development of appropriate bioinks is a complex task, dependent on the mechanical and biochemical requirements of the final construct and the type of printer used for fabrication. The two most common tissue printers are micro-extrusion and digital light projection printers. Here we briefly discuss the required characteristics of a bioink for each of these printing processes. However, physical printing is only a short window in the lifespan of a printed construct—the system must support and facilitate cellular development after it is printed. To that end, we provide a broad overview of some of the biological molecules currently used as bioinks. Each molecule has advantages for specific tissues/cells, and potential disadvantages are discussed, along with examples of their current use in the field. Notably, it is stressed that active researchers are trending towards the use of composite bioinks. Utilizing the strengths from multiple materials is highlighted as a key component of bioink development.Kelsey WillsonAnthony AtalaJames J. YooMDPI AGarticlebioprintingbioink3D printingMicrobiologyQR1-502ENBiomolecules, Vol 11, Iss 1593, p 1593 (2021)
institution DOAJ
collection DOAJ
language EN
topic bioprinting
bioink
3D printing
Microbiology
QR1-502
spellingShingle bioprinting
bioink
3D printing
Microbiology
QR1-502
Kelsey Willson
Anthony Atala
James J. Yoo
Bioprinting Au Natural: The Biologics of Bioinks
description The development of appropriate bioinks is a complex task, dependent on the mechanical and biochemical requirements of the final construct and the type of printer used for fabrication. The two most common tissue printers are micro-extrusion and digital light projection printers. Here we briefly discuss the required characteristics of a bioink for each of these printing processes. However, physical printing is only a short window in the lifespan of a printed construct—the system must support and facilitate cellular development after it is printed. To that end, we provide a broad overview of some of the biological molecules currently used as bioinks. Each molecule has advantages for specific tissues/cells, and potential disadvantages are discussed, along with examples of their current use in the field. Notably, it is stressed that active researchers are trending towards the use of composite bioinks. Utilizing the strengths from multiple materials is highlighted as a key component of bioink development.
format article
author Kelsey Willson
Anthony Atala
James J. Yoo
author_facet Kelsey Willson
Anthony Atala
James J. Yoo
author_sort Kelsey Willson
title Bioprinting Au Natural: The Biologics of Bioinks
title_short Bioprinting Au Natural: The Biologics of Bioinks
title_full Bioprinting Au Natural: The Biologics of Bioinks
title_fullStr Bioprinting Au Natural: The Biologics of Bioinks
title_full_unstemmed Bioprinting Au Natural: The Biologics of Bioinks
title_sort bioprinting au natural: the biologics of bioinks
publisher MDPI AG
publishDate 2021
url https://doaj.org/article/74c00ddd7e5f4be992c59002fb96c175
work_keys_str_mv AT kelseywillson bioprintingaunaturalthebiologicsofbioinks
AT anthonyatala bioprintingaunaturalthebiologicsofbioinks
AT jamesjyoo bioprintingaunaturalthebiologicsofbioinks
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