Exaggeration of Non-Culprit Coronary Artery Stenosis in the Setting of Primary Percutaneous Coronary Intervention: A Single Center Observational Study

Fahmi Othman,1 Abdul Rehman Abid,1 Awad AlQahtani,1 Abdurrazzak Gehani,2 Jassim Al Suwaidi,1 Abdulrahman Arabi1 1Heart Hospital, Hamad Medical Corporation, Doha, Qatar; 2Al-Ahli Hospital, Doha, QatarCorrespondence: Fahmi OthmanHeart Hospital, Hamad Medical Corporation, PO Box 3050, Doha, QatarTel +9...

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Main Authors:	Othman F, Abid AR, AlQahtani A, Gehani A, Al Suwaidi J, Arabi A
Format:	article
Language:	EN
Published:	Dove Medical Press 2021
Subjects:	acute myocardial infarction coronary angiogram minimal lumen diameter non culprit lesion primary percutaneous coronary intervention Diseases of the circulatory (Cardiovascular) system RC666-701
Online Access:	https://doaj.org/article/74c65cb6a28e499cb86fddae7b4e8805
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spelling	oai:doaj.org-article:74c65cb6a28e499cb86fddae7b4e88052021-11-16T18:47:50ZExaggeration of Non-Culprit Coronary Artery Stenosis in the Setting of Primary Percutaneous Coronary Intervention: A Single Center Observational Study1179-8475https://doaj.org/article/74c65cb6a28e499cb86fddae7b4e88052021-11-01T00:00:00Zhttps://www.dovepress.com/exaggeration-of-non-culprit-coronary-artery-stenosis-in-the-setting-of-peer-reviewed-fulltext-article-RRCChttps://doaj.org/toc/1179-8475Fahmi Othman,1 Abdul Rehman Abid,1 Awad AlQahtani,1 Abdurrazzak Gehani,2 Jassim Al Suwaidi,1 Abdulrahman Arabi1 1Heart Hospital, Hamad Medical Corporation, Doha, Qatar; 2Al-Ahli Hospital, Doha, QatarCorrespondence: Fahmi OthmanHeart Hospital, Hamad Medical Corporation, PO Box 3050, Doha, QatarTel +97466580459Email fothman@hamad.qaObjective: We sought to evaluate if the non-culprit coronary artery stenosis severity is affected by primary percutaneous coronary intervention (PPCI) compared with non-PPCI settings.Methods: Review of all the PPCI angiograms was performed at our catheterization laboratory between 15th October 2013 and 15th October 2014. All patients with severe multi-vessel coronary artery disease (MV CAD) who underwent second angiograms (either during the same admission or after discharge) were analyzed. Non-culprit lesions in the PPCI and non-PPCI angiograms were compared. Two investigators blinded to the procedure dates analyzed the severity of the lesions using validated quantitative coronary angiography software (QCA).Results: Among 777 patients who underwent PPCI, 458 had multi-vessel disease. Additional angiography to treat non-culprit lesions was performed in 104, of these, 69 patients had a combined total of 74 lesions suitable for QCA analysis. The second angiogram was performed during the same admission (mean 4± 2.7 days) and after discharge (mean 115± 84 days) for 48 and 21 patients, respectively. Compared to PPCI angiograms, the non-PPCI angiograms showed a statistically significant reduction in the percentage of stenosis (71.6± 14.4% vs 64.5± 14.4%, p≤ 0.001), and an increase in minimal luminal diameter (0.82± 0.45 mm vs 1.00± 0.44 mm, p≤ 0.001) of non-culprit lesion. However, no significant difference was observed in the reference diameter (2.89± 0.69 mm vs 2.83± 0.64 mm, p=0.1) of the non-culprit lesion in both angiograms. Furthermore, these differences in the lesion parameters remain constant whether the second angiogram was performed during the same admission or performed after discharge (73.3± 14% and 66.2± 12.9% vs 68.4± 15% and 61.2± 16%, p=0.1).Conclusion: The severity of non-culprit lesion is exaggerated in the PPCI setting. The non-culprit lesion exaggeration remains constant whether the second angiogram was performed early within a few days or later after several weeks.Keywords: acute myocardial infarction, coronary angiogram, minimal lumen diameter, non-culprit lesion, primary percutaneous coronary interventionOthman FAbid ARAlQahtani AGehani AAl Suwaidi JArabi ADove Medical Pressarticleacute myocardial infarctioncoronary angiogramminimal lumen diameternon culprit lesionprimary percutaneous coronary interventionDiseases of the circulatory (Cardiovascular) systemRC666-701ENResearch Reports in Clinical Cardiology, Vol Volume 12, Pp 67-73 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	acute myocardial infarction coronary angiogram minimal lumen diameter non culprit lesion primary percutaneous coronary intervention Diseases of the circulatory (Cardiovascular) system RC666-701
spellingShingle	acute myocardial infarction coronary angiogram minimal lumen diameter non culprit lesion primary percutaneous coronary intervention Diseases of the circulatory (Cardiovascular) system RC666-701 Othman F Abid AR AlQahtani A Gehani A Al Suwaidi J Arabi A Exaggeration of Non-Culprit Coronary Artery Stenosis in the Setting of Primary Percutaneous Coronary Intervention: A Single Center Observational Study
description	Fahmi Othman,1 Abdul Rehman Abid,1 Awad AlQahtani,1 Abdurrazzak Gehani,2 Jassim Al Suwaidi,1 Abdulrahman Arabi1 1Heart Hospital, Hamad Medical Corporation, Doha, Qatar; 2Al-Ahli Hospital, Doha, QatarCorrespondence: Fahmi OthmanHeart Hospital, Hamad Medical Corporation, PO Box 3050, Doha, QatarTel +97466580459Email fothman@hamad.qaObjective: We sought to evaluate if the non-culprit coronary artery stenosis severity is affected by primary percutaneous coronary intervention (PPCI) compared with non-PPCI settings.Methods: Review of all the PPCI angiograms was performed at our catheterization laboratory between 15th October 2013 and 15th October 2014. All patients with severe multi-vessel coronary artery disease (MV CAD) who underwent second angiograms (either during the same admission or after discharge) were analyzed. Non-culprit lesions in the PPCI and non-PPCI angiograms were compared. Two investigators blinded to the procedure dates analyzed the severity of the lesions using validated quantitative coronary angiography software (QCA).Results: Among 777 patients who underwent PPCI, 458 had multi-vessel disease. Additional angiography to treat non-culprit lesions was performed in 104, of these, 69 patients had a combined total of 74 lesions suitable for QCA analysis. The second angiogram was performed during the same admission (mean 4± 2.7 days) and after discharge (mean 115± 84 days) for 48 and 21 patients, respectively. Compared to PPCI angiograms, the non-PPCI angiograms showed a statistically significant reduction in the percentage of stenosis (71.6± 14.4% vs 64.5± 14.4%, p≤ 0.001), and an increase in minimal luminal diameter (0.82± 0.45 mm vs 1.00± 0.44 mm, p≤ 0.001) of non-culprit lesion. However, no significant difference was observed in the reference diameter (2.89± 0.69 mm vs 2.83± 0.64 mm, p=0.1) of the non-culprit lesion in both angiograms. Furthermore, these differences in the lesion parameters remain constant whether the second angiogram was performed during the same admission or performed after discharge (73.3± 14% and 66.2± 12.9% vs 68.4± 15% and 61.2± 16%, p=0.1).Conclusion: The severity of non-culprit lesion is exaggerated in the PPCI setting. The non-culprit lesion exaggeration remains constant whether the second angiogram was performed early within a few days or later after several weeks.Keywords: acute myocardial infarction, coronary angiogram, minimal lumen diameter, non-culprit lesion, primary percutaneous coronary intervention
format	article
author	Othman F Abid AR AlQahtani A Gehani A Al Suwaidi J Arabi A
author_facet	Othman F Abid AR AlQahtani A Gehani A Al Suwaidi J Arabi A
author_sort	Othman F
title	Exaggeration of Non-Culprit Coronary Artery Stenosis in the Setting of Primary Percutaneous Coronary Intervention: A Single Center Observational Study
title_short	Exaggeration of Non-Culprit Coronary Artery Stenosis in the Setting of Primary Percutaneous Coronary Intervention: A Single Center Observational Study
title_full	Exaggeration of Non-Culprit Coronary Artery Stenosis in the Setting of Primary Percutaneous Coronary Intervention: A Single Center Observational Study
title_fullStr	Exaggeration of Non-Culprit Coronary Artery Stenosis in the Setting of Primary Percutaneous Coronary Intervention: A Single Center Observational Study
title_full_unstemmed	Exaggeration of Non-Culprit Coronary Artery Stenosis in the Setting of Primary Percutaneous Coronary Intervention: A Single Center Observational Study
title_sort	exaggeration of non-culprit coronary artery stenosis in the setting of primary percutaneous coronary intervention: a single center observational study
publisher	Dove Medical Press
publishDate	2021
url	https://doaj.org/article/74c65cb6a28e499cb86fddae7b4e8805
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Exaggeration of Non-Culprit Coronary Artery Stenosis in the Setting of Primary Percutaneous Coronary Intervention: A Single Center Observational Study

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