Anillin propels myosin-independent constriction of actin rings

Cytokinetic ring constriction during cell division requires actin but curiously is independent of myosin in many organisms. Here, the authors show that anillin, a protein enriched in the contractile ring, is a non-motor actin crosslinker that generates contractile force in lieu of a molecular motor.

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Autores principales: Ondřej Kučera, Valerie Siahaan, Daniel Janda, Sietske H. Dijkstra, Eliška Pilátová, Eva Zatecka, Stefan Diez, Marcus Braun, Zdenek Lansky
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/74ce9585db5b41f6ae365c30fb44216c
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spelling oai:doaj.org-article:74ce9585db5b41f6ae365c30fb44216c2021-12-02T16:23:44ZAnillin propels myosin-independent constriction of actin rings10.1038/s41467-021-24474-12041-1723https://doaj.org/article/74ce9585db5b41f6ae365c30fb44216c2021-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-24474-1https://doaj.org/toc/2041-1723Cytokinetic ring constriction during cell division requires actin but curiously is independent of myosin in many organisms. Here, the authors show that anillin, a protein enriched in the contractile ring, is a non-motor actin crosslinker that generates contractile force in lieu of a molecular motor.Ondřej KučeraValerie SiahaanDaniel JandaSietske H. DijkstraEliška PilátováEva ZateckaStefan DiezMarcus BraunZdenek LanskyNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Ondřej Kučera
Valerie Siahaan
Daniel Janda
Sietske H. Dijkstra
Eliška Pilátová
Eva Zatecka
Stefan Diez
Marcus Braun
Zdenek Lansky
Anillin propels myosin-independent constriction of actin rings
description Cytokinetic ring constriction during cell division requires actin but curiously is independent of myosin in many organisms. Here, the authors show that anillin, a protein enriched in the contractile ring, is a non-motor actin crosslinker that generates contractile force in lieu of a molecular motor.
format article
author Ondřej Kučera
Valerie Siahaan
Daniel Janda
Sietske H. Dijkstra
Eliška Pilátová
Eva Zatecka
Stefan Diez
Marcus Braun
Zdenek Lansky
author_facet Ondřej Kučera
Valerie Siahaan
Daniel Janda
Sietske H. Dijkstra
Eliška Pilátová
Eva Zatecka
Stefan Diez
Marcus Braun
Zdenek Lansky
author_sort Ondřej Kučera
title Anillin propels myosin-independent constriction of actin rings
title_short Anillin propels myosin-independent constriction of actin rings
title_full Anillin propels myosin-independent constriction of actin rings
title_fullStr Anillin propels myosin-independent constriction of actin rings
title_full_unstemmed Anillin propels myosin-independent constriction of actin rings
title_sort anillin propels myosin-independent constriction of actin rings
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/74ce9585db5b41f6ae365c30fb44216c
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