Anillin propels myosin-independent constriction of actin rings
Cytokinetic ring constriction during cell division requires actin but curiously is independent of myosin in many organisms. Here, the authors show that anillin, a protein enriched in the contractile ring, is a non-motor actin crosslinker that generates contractile force in lieu of a molecular motor.
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Nature Portfolio
2021
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oai:doaj.org-article:74ce9585db5b41f6ae365c30fb44216c2021-12-02T16:23:44ZAnillin propels myosin-independent constriction of actin rings10.1038/s41467-021-24474-12041-1723https://doaj.org/article/74ce9585db5b41f6ae365c30fb44216c2021-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-24474-1https://doaj.org/toc/2041-1723Cytokinetic ring constriction during cell division requires actin but curiously is independent of myosin in many organisms. Here, the authors show that anillin, a protein enriched in the contractile ring, is a non-motor actin crosslinker that generates contractile force in lieu of a molecular motor.Ondřej KučeraValerie SiahaanDaniel JandaSietske H. DijkstraEliška PilátováEva ZateckaStefan DiezMarcus BraunZdenek LanskyNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-12 (2021) |
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Science Q |
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Science Q Ondřej Kučera Valerie Siahaan Daniel Janda Sietske H. Dijkstra Eliška Pilátová Eva Zatecka Stefan Diez Marcus Braun Zdenek Lansky Anillin propels myosin-independent constriction of actin rings |
description |
Cytokinetic ring constriction during cell division requires actin but curiously is independent of myosin in many organisms. Here, the authors show that anillin, a protein enriched in the contractile ring, is a non-motor actin crosslinker that generates contractile force in lieu of a molecular motor. |
format |
article |
author |
Ondřej Kučera Valerie Siahaan Daniel Janda Sietske H. Dijkstra Eliška Pilátová Eva Zatecka Stefan Diez Marcus Braun Zdenek Lansky |
author_facet |
Ondřej Kučera Valerie Siahaan Daniel Janda Sietske H. Dijkstra Eliška Pilátová Eva Zatecka Stefan Diez Marcus Braun Zdenek Lansky |
author_sort |
Ondřej Kučera |
title |
Anillin propels myosin-independent constriction of actin rings |
title_short |
Anillin propels myosin-independent constriction of actin rings |
title_full |
Anillin propels myosin-independent constriction of actin rings |
title_fullStr |
Anillin propels myosin-independent constriction of actin rings |
title_full_unstemmed |
Anillin propels myosin-independent constriction of actin rings |
title_sort |
anillin propels myosin-independent constriction of actin rings |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/74ce9585db5b41f6ae365c30fb44216c |
work_keys_str_mv |
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_version_ |
1718384116764770304 |