High-throughput behavioral screen in C. elegans reveals Parkinson’s disease drug candidates
Salman Sohrabi et al. develop an automated, high-throughput assay to study spasm-like curling behavior in C. elegans, which is related to motor control symptoms in Parkinson’s disease. They apply this screening approach to identify four candidate drugs for potential late-in-life interventions for Pa...
Guardado en:
Autores principales: | Salman Sohrabi, Danielle E. Mor, Rachel Kaletsky, William Keyes, Coleen T. Murphy |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/74da37c3af4d4181ad273528c6947316 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Large-scale microfluidics providing high-resolution and high-throughput screening of Caenorhabditis elegans poly-glutamine aggregation model
por: Sudip Mondal, et al.
Publicado: (2016) -
An ultra high-throughput, whole-animal screen for small molecule modulators of a specific genetic pathway in Caenorhabditis elegans.
por: Chi K Leung, et al.
Publicado: (2013) -
Integrated network analysis identifying potential novel drug candidates and targets for Parkinson's disease
por: Pusheng Quan, et al.
Publicado: (2021) -
A versatile, automated and high-throughput drug screening platform for zebrafish embryos
por: Alexandra Lubin, et al.
Publicado: (2021) -
Analysis of Static Molecular Gradients in a High-Throughput Drug Screening Microfluidic Assay
por: Roman G. Szafran, et al.
Publicado: (2021)