[46] Cognitive transrectal ultrasonography-guided targeted prostate needle biopsies based on multi-parametric magnetic resonance imaging findings: Initial experience

Objective: To report an initial experience of cognitive transrectal ultrasonography-guided targeted prostate needle biopsies based on multi-parametric magnetic resonance imaging (mpMRI) findings. Random biopsy of the prostate is a crude way to identify prostate cancer hoping to hit the area of disea...

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Autores principales:	Muhammad Bulbul, R. Ghandour, H. Hussein, M. Haddad
Formato:	article
Lenguaje:	EN
Publicado:	Taylor & Francis Group 2018
Materias:	Diseases of the genitourinary system. Urology RC870-923
Acceso en línea:	https://doaj.org/article/74e6569951694d808136554469b97b66
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spelling	oai:doaj.org-article:74e6569951694d808136554469b97b662021-12-02T10:36:47Z[46] Cognitive transrectal ultrasonography-guided targeted prostate needle biopsies based on multi-parametric magnetic resonance imaging findings: Initial experience2090-598X10.1016/j.aju.2018.10.093https://doaj.org/article/74e6569951694d808136554469b97b662018-11-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S2090598X18301876https://doaj.org/toc/2090-598XObjective: To report an initial experience of cognitive transrectal ultrasonography-guided targeted prostate needle biopsies based on multi-parametric magnetic resonance imaging (mpMRI) findings. Random biopsy of the prostate is a crude way to identify prostate cancer hoping to hit the area of disease and hence the yield has never exceeded 30%. The introduction of mpMRI has tremendously enhanced our ability to identify specific suspicious areas with significant disease [Prostate Imaging - Reporting and Data System (PI-RADS) 4 and 5] and to target those areas thus improving the detection of significant disease with fewer biopsies. Methods: In all, 97 consecutive patients with elevated prostate-specific antigen levels and suspicious mpMRI underwent targeted biopsies from the suspicious lesion (∼five) and two random biopsies from the non-suspicious areas. The biopsies were performed using cognitive identification of the suspected area on MRI by a team comprised of a Urologist and Radiologist. All patients had routine pre-biopsy preparation. Results: In all, 55 of 97 patients (57%) had positive biopsies, whilst 41/97 patients (42%) had negative biopsies, and two patients had atypical small acinar proliferation. The median number of cores taken was seven. Of the 55 patients with positive biopsies, 42 had significant Gleason grade ⩾7 disease, 27 had bilateral disease and in 11 of these 27 one contralateral side was negative on MRI but positive at biopsy. Conclusion: Cognitive-targeted biopsies of the prostate based on pre-biopsy MRI mapping for suspicious areas has tremendously enhanced our yield of important disease detection and not insignificant ones. In addition, this is done with fewer biopsies thus reducing potential complications.Muhammad BulbulR. GhandourH. HusseinM. HaddadTaylor & Francis GrouparticleDiseases of the genitourinary system. UrologyRC870-923ENArab Journal of Urology, Vol 16, Iss , Pp S22- (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Diseases of the genitourinary system. Urology RC870-923
spellingShingle	Diseases of the genitourinary system. Urology RC870-923 Muhammad Bulbul R. Ghandour H. Hussein M. Haddad [46] Cognitive transrectal ultrasonography-guided targeted prostate needle biopsies based on multi-parametric magnetic resonance imaging findings: Initial experience
description	Objective: To report an initial experience of cognitive transrectal ultrasonography-guided targeted prostate needle biopsies based on multi-parametric magnetic resonance imaging (mpMRI) findings. Random biopsy of the prostate is a crude way to identify prostate cancer hoping to hit the area of disease and hence the yield has never exceeded 30%. The introduction of mpMRI has tremendously enhanced our ability to identify specific suspicious areas with significant disease [Prostate Imaging - Reporting and Data System (PI-RADS) 4 and 5] and to target those areas thus improving the detection of significant disease with fewer biopsies. Methods: In all, 97 consecutive patients with elevated prostate-specific antigen levels and suspicious mpMRI underwent targeted biopsies from the suspicious lesion (∼five) and two random biopsies from the non-suspicious areas. The biopsies were performed using cognitive identification of the suspected area on MRI by a team comprised of a Urologist and Radiologist. All patients had routine pre-biopsy preparation. Results: In all, 55 of 97 patients (57%) had positive biopsies, whilst 41/97 patients (42%) had negative biopsies, and two patients had atypical small acinar proliferation. The median number of cores taken was seven. Of the 55 patients with positive biopsies, 42 had significant Gleason grade ⩾7 disease, 27 had bilateral disease and in 11 of these 27 one contralateral side was negative on MRI but positive at biopsy. Conclusion: Cognitive-targeted biopsies of the prostate based on pre-biopsy MRI mapping for suspicious areas has tremendously enhanced our yield of important disease detection and not insignificant ones. In addition, this is done with fewer biopsies thus reducing potential complications.
format	article
author	Muhammad Bulbul R. Ghandour H. Hussein M. Haddad
author_facet	Muhammad Bulbul R. Ghandour H. Hussein M. Haddad
author_sort	Muhammad Bulbul
title	[46] Cognitive transrectal ultrasonography-guided targeted prostate needle biopsies based on multi-parametric magnetic resonance imaging findings: Initial experience
title_short	[46] Cognitive transrectal ultrasonography-guided targeted prostate needle biopsies based on multi-parametric magnetic resonance imaging findings: Initial experience
title_full	[46] Cognitive transrectal ultrasonography-guided targeted prostate needle biopsies based on multi-parametric magnetic resonance imaging findings: Initial experience
title_fullStr	[46] Cognitive transrectal ultrasonography-guided targeted prostate needle biopsies based on multi-parametric magnetic resonance imaging findings: Initial experience
title_full_unstemmed	[46] Cognitive transrectal ultrasonography-guided targeted prostate needle biopsies based on multi-parametric magnetic resonance imaging findings: Initial experience
title_sort	[46] cognitive transrectal ultrasonography-guided targeted prostate needle biopsies based on multi-parametric magnetic resonance imaging findings: initial experience
publisher	Taylor & Francis Group
publishDate	2018
url	https://doaj.org/article/74e6569951694d808136554469b97b66
work_keys_str_mv	AT muhammadbulbul 46cognitivetransrectalultrasonographyguidedtargetedprostateneedlebiopsiesbasedonmultiparametricmagneticresonanceimagingfindingsinitialexperience AT rghandour 46cognitivetransrectalultrasonographyguidedtargetedprostateneedlebiopsiesbasedonmultiparametricmagneticresonanceimagingfindingsinitialexperience AT hhussein 46cognitivetransrectalultrasonographyguidedtargetedprostateneedlebiopsiesbasedonmultiparametricmagneticresonanceimagingfindingsinitialexperience AT mhaddad 46cognitivetransrectalultrasonographyguidedtargetedprostateneedlebiopsiesbasedonmultiparametricmagneticresonanceimagingfindingsinitialexperience
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[46] Cognitive transrectal ultrasonography-guided targeted prostate needle biopsies based on multi-parametric magnetic resonance imaging findings: Initial experience

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