Two-component latency distributions indicate two-step vesicular release at simple glutamatergic synapses
Traditionally, synaptic release latency has been viewed as constant. Here, at parallel fiber-interneuron synapses, authors see that with sustained release emerges a slow component of increased latencies, which can be simulated with a 2-step model comprised of vesicle docking followed by release.
Enregistré dans:
Auteurs principaux: | Takafumi Miki, Yukihiro Nakamura, Gerardo Malagon, Erwin Neher, Alain Marty |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2018
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/74ed8df94cbc4fd0a111f0e6a354cd32 |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
Segregation of glutamatergic and cholinergic transmission at the mixed motoneuron Renshaw cell synapse
par: Boris Lamotte d’Incamps, et autres
Publié: (2017) -
Elimination of the vesicular acetylcholine transporter in the striatum reveals regulation of behaviour by cholinergic-glutamatergic co-transmission.
par: Monica S Guzman, et autres
Publié: (2011) -
Opponent vesicular transporters regulate the strength of glutamatergic neurotransmission in a C. elegans sensory circuit
par: Jung-Hwan Choi, et autres
Publié: (2021) -
Evolutionarily Established Palmitoylation-Dependent Regulatory Mechanisms of the Vertebrate Glutamatergic Synapse and Diseases Caused by Their Disruption
par: Takashi Hayashi
Publié: (2021) -
VGLUT1 functions as a glutamate/proton exchanger with chloride channel activity in hippocampal glutamatergic synapses
par: Magalie Martineau, et autres
Publié: (2017)