Two-component latency distributions indicate two-step vesicular release at simple glutamatergic synapses

Traditionally, synaptic release latency has been viewed as constant. Here, at parallel fiber-interneuron  synapses, authors see that with sustained release emerges a slow component of increased latencies, which can be simulated with a 2-step model comprised of vesicle docking followed by release.

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Auteurs principaux: Takafumi Miki, Yukihiro Nakamura, Gerardo Malagon, Erwin Neher, Alain Marty
Format: article
Langue:EN
Publié: Nature Portfolio 2018
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Accès en ligne:https://doaj.org/article/74ed8df94cbc4fd0a111f0e6a354cd32
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