Adipose tissue-derived neurotrophic factor 3 regulates sympathetic innervation and thermogenesis in adipose tissue

Activation of brown adipose tissue thermogenesis increases energy expenditure and promotes weight loss in mice. Here the authors identify neurotrophic factor neurotrophin 3 (NT-3) as an adipokine that regulates sympathetic nervous system growth and innervation in adipose tissue and increases white a...

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Auteurs principaux: Xin Cui, Jia Jing, Rui Wu, Qiang Cao, Fenfen Li, Ke Li, Shirong Wang, Liqing Yu, Gary Schwartz, Huidong Shi, Bingzhong Xue, Hang Shi
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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Accès en ligne:https://doaj.org/article/74f4186b66d4405aa52f8f0ea75e6eb1
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Résumé:Activation of brown adipose tissue thermogenesis increases energy expenditure and promotes weight loss in mice. Here the authors identify neurotrophic factor neurotrophin 3 (NT-3) as an adipokine that regulates sympathetic nervous system growth and innervation in adipose tissue and increases white adipose beiging.