Adipose tissue-derived neurotrophic factor 3 regulates sympathetic innervation and thermogenesis in adipose tissue

Activation of brown adipose tissue thermogenesis increases energy expenditure and promotes weight loss in mice. Here the authors identify neurotrophic factor neurotrophin 3 (NT-3) as an adipokine that regulates sympathetic nervous system growth and innervation in adipose tissue and increases white a...

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Autores principales: Xin Cui, Jia Jing, Rui Wu, Qiang Cao, Fenfen Li, Ke Li, Shirong Wang, Liqing Yu, Gary Schwartz, Huidong Shi, Bingzhong Xue, Hang Shi
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/74f4186b66d4405aa52f8f0ea75e6eb1
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spelling oai:doaj.org-article:74f4186b66d4405aa52f8f0ea75e6eb12021-12-02T14:55:15ZAdipose tissue-derived neurotrophic factor 3 regulates sympathetic innervation and thermogenesis in adipose tissue10.1038/s41467-021-25766-22041-1723https://doaj.org/article/74f4186b66d4405aa52f8f0ea75e6eb12021-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-25766-2https://doaj.org/toc/2041-1723Activation of brown adipose tissue thermogenesis increases energy expenditure and promotes weight loss in mice. Here the authors identify neurotrophic factor neurotrophin 3 (NT-3) as an adipokine that regulates sympathetic nervous system growth and innervation in adipose tissue and increases white adipose beiging.Xin CuiJia JingRui WuQiang CaoFenfen LiKe LiShirong WangLiqing YuGary SchwartzHuidong ShiBingzhong XueHang ShiNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Xin Cui
Jia Jing
Rui Wu
Qiang Cao
Fenfen Li
Ke Li
Shirong Wang
Liqing Yu
Gary Schwartz
Huidong Shi
Bingzhong Xue
Hang Shi
Adipose tissue-derived neurotrophic factor 3 regulates sympathetic innervation and thermogenesis in adipose tissue
description Activation of brown adipose tissue thermogenesis increases energy expenditure and promotes weight loss in mice. Here the authors identify neurotrophic factor neurotrophin 3 (NT-3) as an adipokine that regulates sympathetic nervous system growth and innervation in adipose tissue and increases white adipose beiging.
format article
author Xin Cui
Jia Jing
Rui Wu
Qiang Cao
Fenfen Li
Ke Li
Shirong Wang
Liqing Yu
Gary Schwartz
Huidong Shi
Bingzhong Xue
Hang Shi
author_facet Xin Cui
Jia Jing
Rui Wu
Qiang Cao
Fenfen Li
Ke Li
Shirong Wang
Liqing Yu
Gary Schwartz
Huidong Shi
Bingzhong Xue
Hang Shi
author_sort Xin Cui
title Adipose tissue-derived neurotrophic factor 3 regulates sympathetic innervation and thermogenesis in adipose tissue
title_short Adipose tissue-derived neurotrophic factor 3 regulates sympathetic innervation and thermogenesis in adipose tissue
title_full Adipose tissue-derived neurotrophic factor 3 regulates sympathetic innervation and thermogenesis in adipose tissue
title_fullStr Adipose tissue-derived neurotrophic factor 3 regulates sympathetic innervation and thermogenesis in adipose tissue
title_full_unstemmed Adipose tissue-derived neurotrophic factor 3 regulates sympathetic innervation and thermogenesis in adipose tissue
title_sort adipose tissue-derived neurotrophic factor 3 regulates sympathetic innervation and thermogenesis in adipose tissue
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/74f4186b66d4405aa52f8f0ea75e6eb1
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