Constitutive PGC-1α overexpression in skeletal muscle does not protect from age-dependent decline in neurogenesis
Abstract Aerobic exercise prevents age-dependent decline in cognition and hippocampal neurogenesis. The transcription factor peroxisome proliferator-activated receptor gamma co-activator 1-alpha (PGC-1α) mediates many of the exercise-induced benefits in skeletal muscle, including the release of fact...
Guardado en:
Autores principales: | Lars Karlsson, María Nazareth González-Alvarado, Reza Motalleb, Klas Blomgren, Mats Börjesson, Hans Georg Kuhn |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2019
|
Materias: | |
Acceso en línea: | https://doaj.org/article/74f670ac4f37438ab1c911718eab4057 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Skeletal muscle PGC-1α1 reroutes kynurenine metabolism to increase energy efficiency and fatigue-resistance
por: Leandro Z. Agudelo, et al.
Publicado: (2019) -
Constitutive overexpression of muscarinic receptors leads to vagal hyperreactivity.
por: Angelo Livolsi, et al.
Publicado: (2010) -
Decline in Constitutive Proliferative Activity in the Zebrafish Retina with Ageing
por: Ismael Hernández-Núñez, et al.
Publicado: (2021) -
Casos prácticos del PGC y PGC PyMES y sus implicaciones fiscales /
por: Martínez Alfonso, Antonio P.
Publicado: (2016) -
Effect of metformin treatment on memory and hippocampal neurogenesis decline correlated with oxidative stress induced by methotrexate in rats
por: Nataya Sritawan, et al.
Publicado: (2021)