IgA nephropathy with wilson's disease: A case report and literature review
The most common glomerulonephritis seen in the world is immunoglobulin A nephropathy (IgAN). It can be primary or secondary associated with various conditions like Chronic Liver disease, Crohn's disease, neoplasms, etc. However, IgAN secondary to Wilson's disease is very rare. A 9 year old...
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Wolters Kluwer Medknow Publications
2021
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oai:doaj.org-article:74f70a6cf9a146479de418a857b56b0f2021-12-02T17:28:22ZIgA nephropathy with wilson's disease: A case report and literature review0971-40651998-366210.4103/ijn.IJN_227_20https://doaj.org/article/74f70a6cf9a146479de418a857b56b0f2021-01-01T00:00:00Zhttp://www.indianjnephrol.org/article.asp?issn=0971-4065;year=2021;volume=31;issue=5;spage=474;epage=477;aulast=Bhandarihttps://doaj.org/toc/0971-4065https://doaj.org/toc/1998-3662The most common glomerulonephritis seen in the world is immunoglobulin A nephropathy (IgAN). It can be primary or secondary associated with various conditions like Chronic Liver disease, Crohn's disease, neoplasms, etc. However, IgAN secondary to Wilson's disease is very rare. A 9 year old boy presented with gross hematuria and proteinuria. He had a history of recurrent jaundice in the past. Ultrasonography (USG) whole abdomen showed altered echotexture of the liver with normal-sized kidneys. An extended workup for liver disease was done, and the diagnosis of Wilson's disease was confirmed with decreased serum ceruloplasmin levels, increased urinary copper, and the Kayser–Fleischer ring. Urine routine microscopy showed numerous red blood cells, few red blood cell casts, and mild proteinuria. Renal biopsy showed IgAN. The patient was started on D-penicillamine. On follow-up at 3 months, he showed complete resolution of proteinuria and hematuria. Thus, we suggest that Wilson's disease should be considered as one of the causes of secondary IgAN in pediatric patients with hematuria, proteinuria with liver dysfunction.Gaurav BhandariVaibhav TiwariAnurag GuptaPallav GuptaVinant BhargavaManish MalikAshwani GuptaAnil K BhallaDevinder S RanaWolters Kluwer Medknow Publicationsarticlehematuriaiga nephropathyjaundicekf ringwilson's diseaseDiseases of the genitourinary system. UrologyRC870-923ENIndian Journal of Nephrology, Vol 31, Iss 5, Pp 474-477 (2021) |
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hematuria iga nephropathy jaundice kf ring wilson's disease Diseases of the genitourinary system. Urology RC870-923 |
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hematuria iga nephropathy jaundice kf ring wilson's disease Diseases of the genitourinary system. Urology RC870-923 Gaurav Bhandari Vaibhav Tiwari Anurag Gupta Pallav Gupta Vinant Bhargava Manish Malik Ashwani Gupta Anil K Bhalla Devinder S Rana IgA nephropathy with wilson's disease: A case report and literature review |
| description |
The most common glomerulonephritis seen in the world is immunoglobulin A nephropathy (IgAN). It can be primary or secondary associated with various conditions like Chronic Liver disease, Crohn's disease, neoplasms, etc. However, IgAN secondary to Wilson's disease is very rare. A 9 year old boy presented with gross hematuria and proteinuria. He had a history of recurrent jaundice in the past. Ultrasonography (USG) whole abdomen showed altered echotexture of the liver with normal-sized kidneys. An extended workup for liver disease was done, and the diagnosis of Wilson's disease was confirmed with decreased serum ceruloplasmin levels, increased urinary copper, and the Kayser–Fleischer ring. Urine routine microscopy showed numerous red blood cells, few red blood cell casts, and mild proteinuria. Renal biopsy showed IgAN. The patient was started on D-penicillamine. On follow-up at 3 months, he showed complete resolution of proteinuria and hematuria. Thus, we suggest that Wilson's disease should be considered as one of the causes of secondary IgAN in pediatric patients with hematuria, proteinuria with liver dysfunction. |
| format |
article |
| author |
Gaurav Bhandari Vaibhav Tiwari Anurag Gupta Pallav Gupta Vinant Bhargava Manish Malik Ashwani Gupta Anil K Bhalla Devinder S Rana |
| author_facet |
Gaurav Bhandari Vaibhav Tiwari Anurag Gupta Pallav Gupta Vinant Bhargava Manish Malik Ashwani Gupta Anil K Bhalla Devinder S Rana |
| author_sort |
Gaurav Bhandari |
| title |
IgA nephropathy with wilson's disease: A case report and literature review |
| title_short |
IgA nephropathy with wilson's disease: A case report and literature review |
| title_full |
IgA nephropathy with wilson's disease: A case report and literature review |
| title_fullStr |
IgA nephropathy with wilson's disease: A case report and literature review |
| title_full_unstemmed |
IgA nephropathy with wilson's disease: A case report and literature review |
| title_sort |
iga nephropathy with wilson's disease: a case report and literature review |
| publisher |
Wolters Kluwer Medknow Publications |
| publishDate |
2021 |
| url |
https://doaj.org/article/74f70a6cf9a146479de418a857b56b0f |
| work_keys_str_mv |
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