IMMUNE EPITOPE CONTINUUM OF THE PROTEIN RELATIONSHIPS, POLY- AND AUTOREACTIVITY OF ANTIBODIES

Computer analysis of primary structure for >3300 proteins has shown an opportunity for existence of global immune epitope continuum of protein relationships (IECPR) for eukaryotes, prokaryotes, and viruses. On the basis of IECPR, one may provide new interpretations for immune events, and in p...

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Autor principal:	E. P. Kharchenko
Formato:	article
Lenguaje:	RU
Publicado:	SPb RAACI 2015
Materias:	proteins epitopes antibodies immune regulation immune tolerance vaccines Immunologic diseases. Allergy RC581-607
Acceso en línea:	https://doaj.org/article/7504ac1157a74ed18356d2e3408ac2e7
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spelling	oai:doaj.org-article:7504ac1157a74ed18356d2e3408ac2e72021-11-18T08:03:45ZIMMUNE EPITOPE CONTINUUM OF THE PROTEIN RELATIONSHIPS, POLY- AND AUTOREACTIVITY OF ANTIBODIES1563-06252313-741X10.15789/1563-0625-2015-4-335-346https://doaj.org/article/7504ac1157a74ed18356d2e3408ac2e72015-10-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/925https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XComputer analysis of primary structure for >3300 proteins has shown an opportunity for existence of global immune epitope continuum of protein relationships (IECPR) for eukaryotes, prokaryotes, and viruses. On the basis of IECPR, one may provide new interpretations for immune events, and in particular, to consider them as an additional factor determining poly- and autoreactivity of antibodies, and, respectively, extend the concept of regulatory functions of natural antibodies. For medical practice, the IECPR would be especially useful in cases of search for novel vaccines and immune diagnostic preparations.E. P. KharchenkoSPb RAACIarticleproteinsepitopesantibodiesimmune regulationimmune tolerancevaccinesImmunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 17, Iss 4, Pp 335-346 (2015)
institution	DOAJ
collection	DOAJ
language	RU
topic	proteins epitopes antibodies immune regulation immune tolerance vaccines Immunologic diseases. Allergy RC581-607
spellingShingle	proteins epitopes antibodies immune regulation immune tolerance vaccines Immunologic diseases. Allergy RC581-607 E. P. Kharchenko IMMUNE EPITOPE CONTINUUM OF THE PROTEIN RELATIONSHIPS, POLY- AND AUTOREACTIVITY OF ANTIBODIES
description	Computer analysis of primary structure for >3300 proteins has shown an opportunity for existence of global immune epitope continuum of protein relationships (IECPR) for eukaryotes, prokaryotes, and viruses. On the basis of IECPR, one may provide new interpretations for immune events, and in particular, to consider them as an additional factor determining poly- and autoreactivity of antibodies, and, respectively, extend the concept of regulatory functions of natural antibodies. For medical practice, the IECPR would be especially useful in cases of search for novel vaccines and immune diagnostic preparations.
format	article
author	E. P. Kharchenko
author_facet	E. P. Kharchenko
author_sort	E. P. Kharchenko
title	IMMUNE EPITOPE CONTINUUM OF THE PROTEIN RELATIONSHIPS, POLY- AND AUTOREACTIVITY OF ANTIBODIES
title_short	IMMUNE EPITOPE CONTINUUM OF THE PROTEIN RELATIONSHIPS, POLY- AND AUTOREACTIVITY OF ANTIBODIES
title_full	IMMUNE EPITOPE CONTINUUM OF THE PROTEIN RELATIONSHIPS, POLY- AND AUTOREACTIVITY OF ANTIBODIES
title_fullStr	IMMUNE EPITOPE CONTINUUM OF THE PROTEIN RELATIONSHIPS, POLY- AND AUTOREACTIVITY OF ANTIBODIES
title_full_unstemmed	IMMUNE EPITOPE CONTINUUM OF THE PROTEIN RELATIONSHIPS, POLY- AND AUTOREACTIVITY OF ANTIBODIES
title_sort	immune epitope continuum of the protein relationships, poly- and autoreactivity of antibodies
publisher	SPb RAACI
publishDate	2015
url	https://doaj.org/article/7504ac1157a74ed18356d2e3408ac2e7
work_keys_str_mv	AT epkharchenko immuneepitopecontinuumoftheproteinrelationshipspolyandautoreactivityofantibodies
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IMMUNE EPITOPE CONTINUUM OF THE PROTEIN RELATIONSHIPS, POLY- AND AUTOREACTIVITY OF ANTIBODIES

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