The New Xpert MTB/RIF Ultra: Improving Detection of <italic toggle="yes">Mycobacterium tuberculosis</italic> and Resistance to Rifampin in an Assay Suitable for Point-of-Care Testing

The New Xpert MTB/RIF Ultra: Improving Detection of <italic toggle="yes">Mycobacterium tuberculosis</italic> and Resistance to Rifampin in an Assay Suitable for Point-of-Care Testing

ABSTRACT The Xpert MTB/RIF assay (Xpert) is a rapid test for tuberculosis (TB) and rifampin resistance (RIF-R) suitable for point-of-care testing. However, it has decreased sensitivity in smear-negative sputum, and false identification of RIF-R occasionally occurs. We developed the Xpert MTB/RIF Ult...

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Autores principales: Soumitesh Chakravorty, Ann Marie Simmons, Mazhgan Rowneki, Heta Parmar, Yuan Cao, Jamie Ryan, Padmapriya P. Banada, Srinidhi Deshpande, Shubhada Shenai, Alexander Gall, Jennifer Glass, Barry Krieswirth, Samuel G. Schumacher, Pamela Nabeta, Nestani Tukvadze, Camilla Rodrigues, Alena Skrahina, Elisa Tagliani, Daniela M. Cirillo, Amy Davidow, Claudia M. Denkinger, David Persing, Robert Kwiatkowski, Martin Jones, David Alland
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2017
Materias:
Xpert MTB/RIF Ultra
diagnosis
sensitive
tuberculosis
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/751391a3a1084ef2b8c600d6d58453e0
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