Stress-induced plasticity of dynamic collagen networks

The structure and mechanics of tissues is constantly perturbed by endogenous forces originated from cells. Here the authors show that 3D collagen gels, major components of connective tissues and extracellular matrix, are significantly and irreversibly remodelled by cellular traction forces and by ma...

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Detalles Bibliográficos
Autores principales: Jihan Kim, Jingchen Feng, Christopher A. R. Jones, Xiaoming Mao, Leonard M. Sander, Herbert Levine, Bo Sun
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/75282c6ce4444252a75d97de6f19645f
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Sumario:The structure and mechanics of tissues is constantly perturbed by endogenous forces originated from cells. Here the authors show that 3D collagen gels, major components of connective tissues and extracellular matrix, are significantly and irreversibly remodelled by cellular traction forces and by macroscopic strains.