Stress-induced plasticity of dynamic collagen networks

The structure and mechanics of tissues is constantly perturbed by endogenous forces originated from cells. Here the authors show that 3D collagen gels, major components of connective tissues and extracellular matrix, are significantly and irreversibly remodelled by cellular traction forces and by ma...

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Autores principales: Jihan Kim, Jingchen Feng, Christopher A. R. Jones, Xiaoming Mao, Leonard M. Sander, Herbert Levine, Bo Sun
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/75282c6ce4444252a75d97de6f19645f
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spelling oai:doaj.org-article:75282c6ce4444252a75d97de6f19645f2021-12-02T14:42:37ZStress-induced plasticity of dynamic collagen networks10.1038/s41467-017-01011-72041-1723https://doaj.org/article/75282c6ce4444252a75d97de6f19645f2017-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01011-7https://doaj.org/toc/2041-1723The structure and mechanics of tissues is constantly perturbed by endogenous forces originated from cells. Here the authors show that 3D collagen gels, major components of connective tissues and extracellular matrix, are significantly and irreversibly remodelled by cellular traction forces and by macroscopic strains.Jihan KimJingchen FengChristopher A. R. JonesXiaoming MaoLeonard M. SanderHerbert LevineBo SunNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-7 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Jihan Kim
Jingchen Feng
Christopher A. R. Jones
Xiaoming Mao
Leonard M. Sander
Herbert Levine
Bo Sun
Stress-induced plasticity of dynamic collagen networks
description The structure and mechanics of tissues is constantly perturbed by endogenous forces originated from cells. Here the authors show that 3D collagen gels, major components of connective tissues and extracellular matrix, are significantly and irreversibly remodelled by cellular traction forces and by macroscopic strains.
format article
author Jihan Kim
Jingchen Feng
Christopher A. R. Jones
Xiaoming Mao
Leonard M. Sander
Herbert Levine
Bo Sun
author_facet Jihan Kim
Jingchen Feng
Christopher A. R. Jones
Xiaoming Mao
Leonard M. Sander
Herbert Levine
Bo Sun
author_sort Jihan Kim
title Stress-induced plasticity of dynamic collagen networks
title_short Stress-induced plasticity of dynamic collagen networks
title_full Stress-induced plasticity of dynamic collagen networks
title_fullStr Stress-induced plasticity of dynamic collagen networks
title_full_unstemmed Stress-induced plasticity of dynamic collagen networks
title_sort stress-induced plasticity of dynamic collagen networks
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/75282c6ce4444252a75d97de6f19645f
work_keys_str_mv AT jihankim stressinducedplasticityofdynamiccollagennetworks
AT jingchenfeng stressinducedplasticityofdynamiccollagennetworks
AT christopherarjones stressinducedplasticityofdynamiccollagennetworks
AT xiaomingmao stressinducedplasticityofdynamiccollagennetworks
AT leonardmsander stressinducedplasticityofdynamiccollagennetworks
AT herbertlevine stressinducedplasticityofdynamiccollagennetworks
AT bosun stressinducedplasticityofdynamiccollagennetworks
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