Benign Histopathologic Findings of Endometrium among Perimenopausal Women presenting with Abnormal Uterine Bleeding: A Descriptive Cross-sectional Study

Introduction: Abnormal uterine bleeding is the most common presenting complaint in the perimenopausal age group. Endometrial biopsy obtained by dilatation and curettage is the preferred modality of investigation to determine the causative pathology of abnormal uterine bleeding. The objective of thi...

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Autores principales:	Ramesh Dhakhwa, Rashmi Bhattarai, Jayanti Shah, Archana Shakya, Sailesh Pradhan
Formato:	article
Lenguaje:	EN
Publicado:	Nepal Medical Association 2021
Materias:	abnormal uterine bleeding; histopathology; perimenopausal. Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/753bac0c1271421fbfd17a57f9e143ef
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spelling	oai:doaj.org-article:753bac0c1271421fbfd17a57f9e143ef2021-11-18T19:19:46ZBenign Histopathologic Findings of Endometrium among Perimenopausal Women presenting with Abnormal Uterine Bleeding: A Descriptive Cross-sectional Study10.31729/jnma.71460028-27151815-672Xhttps://doaj.org/article/753bac0c1271421fbfd17a57f9e143ef2021-11-01T00:00:00Zhttp://www.jnma.com.np/jnma/index.php/jnma/article/view/7146https://doaj.org/toc/0028-2715https://doaj.org/toc/1815-672X Introduction: Abnormal uterine bleeding is the most common presenting complaint in the perimenopausal age group. Endometrial biopsy obtained by dilatation and curettage is the preferred modality of investigation to determine the causative pathology of abnormal uterine bleeding. The objective of this study was to find out the prevalence of the benign histopathological findings in perimenopausal women presenting with abnormal uterine bleeding. Methods: This descriptive cross-sectional study was conducted among patients between 1st June 2020 to 30th September 2021. Ethical approval was taken from the Institutional Review Committee of Kathmandu Medical College (reference number: 305202002). Using the convenience sampling method, 96 cases of endometrial biopsies were studied under light microscopy. Data was analyzed using the Statistical Package for the Social Sciences version23.0. Point estimate at 95% Confidence Interval was calculated along with frequency and proportion for binary data. Results: Among the 96 specimens, the prevalence of benign findings was 93 (96.9%) (93-100 at 95% Confidence Interval). Among them, the commonest benign histopathologic spectrum was hormonal imbalance pattern in 40 (41.7%) followed by normal menstrual pattern 35 (36.5%). Five (5.2%) cases showed chronic endometritis. Six (6.2%) cases of endometrial hyperplasia without atypia were identified. Three (3.1%) cases showed endometrial atrophy. Four (4.1%) cases showed endometrial polyp. Conclusions: The prevalence of benign histopathological findings among endometrial biopsies in the study was similar to other studies. Ramesh DhakhwaRashmi BhattaraiJayanti ShahArchana ShakyaSailesh PradhanNepal Medical Associationarticleabnormal uterine bleeding; histopathology; perimenopausal.Medicine (General)R5-920ENJournal of Nepal Medical Association, Vol 59, Iss 243 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	abnormal uterine bleeding; histopathology; perimenopausal. Medicine (General) R5-920
spellingShingle	abnormal uterine bleeding; histopathology; perimenopausal. Medicine (General) R5-920 Ramesh Dhakhwa Rashmi Bhattarai Jayanti Shah Archana Shakya Sailesh Pradhan Benign Histopathologic Findings of Endometrium among Perimenopausal Women presenting with Abnormal Uterine Bleeding: A Descriptive Cross-sectional Study
description	Introduction: Abnormal uterine bleeding is the most common presenting complaint in the perimenopausal age group. Endometrial biopsy obtained by dilatation and curettage is the preferred modality of investigation to determine the causative pathology of abnormal uterine bleeding. The objective of this study was to find out the prevalence of the benign histopathological findings in perimenopausal women presenting with abnormal uterine bleeding. Methods: This descriptive cross-sectional study was conducted among patients between 1st June 2020 to 30th September 2021. Ethical approval was taken from the Institutional Review Committee of Kathmandu Medical College (reference number: 305202002). Using the convenience sampling method, 96 cases of endometrial biopsies were studied under light microscopy. Data was analyzed using the Statistical Package for the Social Sciences version23.0. Point estimate at 95% Confidence Interval was calculated along with frequency and proportion for binary data. Results: Among the 96 specimens, the prevalence of benign findings was 93 (96.9%) (93-100 at 95% Confidence Interval). Among them, the commonest benign histopathologic spectrum was hormonal imbalance pattern in 40 (41.7%) followed by normal menstrual pattern 35 (36.5%). Five (5.2%) cases showed chronic endometritis. Six (6.2%) cases of endometrial hyperplasia without atypia were identified. Three (3.1%) cases showed endometrial atrophy. Four (4.1%) cases showed endometrial polyp. Conclusions: The prevalence of benign histopathological findings among endometrial biopsies in the study was similar to other studies.
format	article
author	Ramesh Dhakhwa Rashmi Bhattarai Jayanti Shah Archana Shakya Sailesh Pradhan
author_facet	Ramesh Dhakhwa Rashmi Bhattarai Jayanti Shah Archana Shakya Sailesh Pradhan
author_sort	Ramesh Dhakhwa
title	Benign Histopathologic Findings of Endometrium among Perimenopausal Women presenting with Abnormal Uterine Bleeding: A Descriptive Cross-sectional Study
title_short	Benign Histopathologic Findings of Endometrium among Perimenopausal Women presenting with Abnormal Uterine Bleeding: A Descriptive Cross-sectional Study
title_full	Benign Histopathologic Findings of Endometrium among Perimenopausal Women presenting with Abnormal Uterine Bleeding: A Descriptive Cross-sectional Study
title_fullStr	Benign Histopathologic Findings of Endometrium among Perimenopausal Women presenting with Abnormal Uterine Bleeding: A Descriptive Cross-sectional Study
title_full_unstemmed	Benign Histopathologic Findings of Endometrium among Perimenopausal Women presenting with Abnormal Uterine Bleeding: A Descriptive Cross-sectional Study
title_sort	benign histopathologic findings of endometrium among perimenopausal women presenting with abnormal uterine bleeding: a descriptive cross-sectional study
publisher	Nepal Medical Association
publishDate	2021
url	https://doaj.org/article/753bac0c1271421fbfd17a57f9e143ef
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Benign Histopathologic Findings of Endometrium among Perimenopausal Women presenting with Abnormal Uterine Bleeding: A Descriptive Cross-sectional Study

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