Production of human CAR-NK cells with lentiviral vectors and functional assessment in vitro

Summary: Although natural killer (NK) cells have become a promising immune effector cell for chimeric antigen receptor (CAR)-based therapy, generating human CAR-NK cells with high transgene efficiency has been challenging. In this protocol, we describe how to generate CAR-NK cells with transduction...

Full description

Saved in:
Bibliographic Details
Main Authors: Ana L. Portillo, Richard Hogg, Ali A. Ashkar
Format: article
Language:EN
Published: Elsevier 2021
Subjects:
Online Access:https://doaj.org/article/7540abfaed4544eaa9ea2867d0c58adb
Tags: Add Tag
No Tags, Be the first to tag this record!