A network of RNA-binding proteins controls translation efficiency to activate anaerobic metabolism

mRNA translation efficiency is regulated in response to stimuli. Here the authors employ mass spectrometry analysis of ribosome fractions and show that under hypoxia, oxygen-sensitive RNA binding proteins enhance the translation efficiency of glycolysis pathway transcripts.

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Autores principales: J. J. David Ho, Nathan C. Balukoff, Phaedra R. Theodoridis, Miling Wang, Jonathan R. Krieger, Jonathan H. Schatz, Stephen Lee
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/754a4b16d6cf4bd486c30441585007ea
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