Derivation and characterisation of endothelial cells from patients with chronic thromboembolic pulmonary hypertension

Derivation and characterisation of endothelial cells from patients with chronic thromboembolic pulmonary hypertension

Abstract Pulmonary endarterectomy (PEA) resected material offers a unique opportunity to develop an in vitro endothelial cell model of chronic thromboembolic pulmonary hypertension (CTEPH). We aimed to comprehensively analyze the endothelial function, molecular signature, and mitochondrial profile o...

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Auteurs principaux: Olga Tura-Ceide, Valérie F. E. D. Smolders, Núria Aventin, Constanza Morén, Mariona Guitart-Mampel, Isabel Blanco, Lucilla Piccari, Jeisson Osorio, Cristina Rodríguez, Montserrat Rigol, Núria Solanes, Andrea Malandrino, Kondababu Kurakula, Marie Jose Goumans, Paul H. A. Quax, Victor I. Peinado, Manuel Castellà, Joan Albert Barberà
Format: article
Langue:EN
Publié: Nature Portfolio 2021
Sujets:
Medicine
R
Science
Q
Accès en ligne:https://doaj.org/article/754ae83577394ffaaec8967753372381
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