A genome-wide association study to detect QTL for commercially important traits in Swiss Large White boars.

The improvement of meat quality and production traits has high priority in the pork industry. Many of these traits show a low to moderate heritability and are difficult and expensive to measure. Their improvement by targeted breeding programs is challenging and requires knowledge of the genetic and...

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Autores principales:	Doreen Becker, Klaus Wimmers, Henning Luther, Andreas Hofer, Tosso Leeb
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2013
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/754af24078ff4e8b8a000997444da2f0
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spelling	oai:doaj.org-article:754af24078ff4e8b8a000997444da2f02021-11-18T07:58:45ZA genome-wide association study to detect QTL for commercially important traits in Swiss Large White boars.1932-620310.1371/journal.pone.0055951https://doaj.org/article/754af24078ff4e8b8a000997444da2f02013-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23393604/?tool=EBIhttps://doaj.org/toc/1932-6203The improvement of meat quality and production traits has high priority in the pork industry. Many of these traits show a low to moderate heritability and are difficult and expensive to measure. Their improvement by targeted breeding programs is challenging and requires knowledge of the genetic and molecular background. For this study we genotyped 192 artificial insemination boars of a commercial line derived from the Swiss Large White breed using the PorcineSNP60 BeadChip with 62,163 evenly spaced SNPs across the pig genome. We obtained 26 estimated breeding values (EBVs) for various traits including exterior, meat quality, reproduction, and production. The subsequent genome-wide association analysis allowed us to identify four QTL with suggestive significance for three of these traits (p-values ranging from 4.99×10⁻⁶ to 2.73×10⁻⁵). Single QTL for the EBVs pH one hour post mortem (pH1) and carcass length were on pig chromosome (SSC) 14 and SSC 2, respectively. Two QTL for the EBV rear view hind legs were on SSC 10 and SSC 16.Doreen BeckerKlaus WimmersHenning LutherAndreas HoferTosso LeebPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 8, Iss 2, p e55951 (2013)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Doreen Becker Klaus Wimmers Henning Luther Andreas Hofer Tosso Leeb A genome-wide association study to detect QTL for commercially important traits in Swiss Large White boars.
description	The improvement of meat quality and production traits has high priority in the pork industry. Many of these traits show a low to moderate heritability and are difficult and expensive to measure. Their improvement by targeted breeding programs is challenging and requires knowledge of the genetic and molecular background. For this study we genotyped 192 artificial insemination boars of a commercial line derived from the Swiss Large White breed using the PorcineSNP60 BeadChip with 62,163 evenly spaced SNPs across the pig genome. We obtained 26 estimated breeding values (EBVs) for various traits including exterior, meat quality, reproduction, and production. The subsequent genome-wide association analysis allowed us to identify four QTL with suggestive significance for three of these traits (p-values ranging from 4.99×10⁻⁶ to 2.73×10⁻⁵). Single QTL for the EBVs pH one hour post mortem (pH1) and carcass length were on pig chromosome (SSC) 14 and SSC 2, respectively. Two QTL for the EBV rear view hind legs were on SSC 10 and SSC 16.
format	article
author	Doreen Becker Klaus Wimmers Henning Luther Andreas Hofer Tosso Leeb
author_facet	Doreen Becker Klaus Wimmers Henning Luther Andreas Hofer Tosso Leeb
author_sort	Doreen Becker
title	A genome-wide association study to detect QTL for commercially important traits in Swiss Large White boars.
title_short	A genome-wide association study to detect QTL for commercially important traits in Swiss Large White boars.
title_full	A genome-wide association study to detect QTL for commercially important traits in Swiss Large White boars.
title_fullStr	A genome-wide association study to detect QTL for commercially important traits in Swiss Large White boars.
title_full_unstemmed	A genome-wide association study to detect QTL for commercially important traits in Swiss Large White boars.
title_sort	genome-wide association study to detect qtl for commercially important traits in swiss large white boars.
publisher	Public Library of Science (PLoS)
publishDate	2013
url	https://doaj.org/article/754af24078ff4e8b8a000997444da2f0
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A genome-wide association study to detect QTL for commercially important traits in Swiss Large White boars.

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