Wisp1 is a circulating factor that stimulates proliferation of adult mouse and human beta cells

The proliferation of pancreatic beta cells decreases with age, partly due to systemic changes. Here the authors identify Wisp1 as a circulating factor enriched in young serum that induces adult beta cell proliferation, supporting the idea that young blood factors may be useful to expand beta cell ma...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Rebeca Fernandez-Ruiz, Ainhoa García-Alamán, Yaiza Esteban, Joan Mir-Coll, Berta Serra-Navarro, Marta Fontcuberta-PiSunyer, Christophe Broca, Mathieu Armanet, Anne Wojtusciszyn, Vardit Kram, Marian F. Young, Josep Vidal, Ramon Gomis, Rosa Gasa
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/75526fb6644249f68e8b4986865a300c
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:75526fb6644249f68e8b4986865a300c
record_format	dspace
spelling	oai:doaj.org-article:75526fb6644249f68e8b4986865a300c2021-12-02T13:57:33ZWisp1 is a circulating factor that stimulates proliferation of adult mouse and human beta cells10.1038/s41467-020-19657-12041-1723https://doaj.org/article/75526fb6644249f68e8b4986865a300c2020-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19657-1https://doaj.org/toc/2041-1723The proliferation of pancreatic beta cells decreases with age, partly due to systemic changes. Here the authors identify Wisp1 as a circulating factor enriched in young serum that induces adult beta cell proliferation, supporting the idea that young blood factors may be useful to expand beta cell mass.Rebeca Fernandez-RuizAinhoa García-AlamánYaiza EstebanJoan Mir-CollBerta Serra-NavarroMarta Fontcuberta-PiSunyerChristophe BrocaMathieu ArmanetAnne WojtusciszynVardit KramMarian F. YoungJosep VidalRamon GomisRosa GasaNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Rebeca Fernandez-Ruiz Ainhoa García-Alamán Yaiza Esteban Joan Mir-Coll Berta Serra-Navarro Marta Fontcuberta-PiSunyer Christophe Broca Mathieu Armanet Anne Wojtusciszyn Vardit Kram Marian F. Young Josep Vidal Ramon Gomis Rosa Gasa Wisp1 is a circulating factor that stimulates proliferation of adult mouse and human beta cells
description	The proliferation of pancreatic beta cells decreases with age, partly due to systemic changes. Here the authors identify Wisp1 as a circulating factor enriched in young serum that induces adult beta cell proliferation, supporting the idea that young blood factors may be useful to expand beta cell mass.
format	article
author	Rebeca Fernandez-Ruiz Ainhoa García-Alamán Yaiza Esteban Joan Mir-Coll Berta Serra-Navarro Marta Fontcuberta-PiSunyer Christophe Broca Mathieu Armanet Anne Wojtusciszyn Vardit Kram Marian F. Young Josep Vidal Ramon Gomis Rosa Gasa
author_facet	Rebeca Fernandez-Ruiz Ainhoa García-Alamán Yaiza Esteban Joan Mir-Coll Berta Serra-Navarro Marta Fontcuberta-PiSunyer Christophe Broca Mathieu Armanet Anne Wojtusciszyn Vardit Kram Marian F. Young Josep Vidal Ramon Gomis Rosa Gasa
author_sort	Rebeca Fernandez-Ruiz
title	Wisp1 is a circulating factor that stimulates proliferation of adult mouse and human beta cells
title_short	Wisp1 is a circulating factor that stimulates proliferation of adult mouse and human beta cells
title_full	Wisp1 is a circulating factor that stimulates proliferation of adult mouse and human beta cells
title_fullStr	Wisp1 is a circulating factor that stimulates proliferation of adult mouse and human beta cells
title_full_unstemmed	Wisp1 is a circulating factor that stimulates proliferation of adult mouse and human beta cells
title_sort	wisp1 is a circulating factor that stimulates proliferation of adult mouse and human beta cells
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/75526fb6644249f68e8b4986865a300c
work_keys_str_mv	AT rebecafernandezruiz wisp1isacirculatingfactorthatstimulatesproliferationofadultmouseandhumanbetacells AT ainhoagarciaalaman wisp1isacirculatingfactorthatstimulatesproliferationofadultmouseandhumanbetacells AT yaizaesteban wisp1isacirculatingfactorthatstimulatesproliferationofadultmouseandhumanbetacells AT joanmircoll wisp1isacirculatingfactorthatstimulatesproliferationofadultmouseandhumanbetacells AT bertaserranavarro wisp1isacirculatingfactorthatstimulatesproliferationofadultmouseandhumanbetacells AT martafontcubertapisunyer wisp1isacirculatingfactorthatstimulatesproliferationofadultmouseandhumanbetacells AT christophebroca wisp1isacirculatingfactorthatstimulatesproliferationofadultmouseandhumanbetacells AT mathieuarmanet wisp1isacirculatingfactorthatstimulatesproliferationofadultmouseandhumanbetacells AT annewojtusciszyn wisp1isacirculatingfactorthatstimulatesproliferationofadultmouseandhumanbetacells AT varditkram wisp1isacirculatingfactorthatstimulatesproliferationofadultmouseandhumanbetacells AT marianfyoung wisp1isacirculatingfactorthatstimulatesproliferationofadultmouseandhumanbetacells AT josepvidal wisp1isacirculatingfactorthatstimulatesproliferationofadultmouseandhumanbetacells AT ramongomis wisp1isacirculatingfactorthatstimulatesproliferationofadultmouseandhumanbetacells AT rosagasa wisp1isacirculatingfactorthatstimulatesproliferationofadultmouseandhumanbetacells
_version_	1718392330791157760

Wisp1 is a circulating factor that stimulates proliferation of adult mouse and human beta cells

Ejemplares similares