Microglial activation increases cocaine self-administration following adolescent nicotine exposure

Adolescents are particularly sensitive to nicotine. Here the authors show that in mice, microglial activation contributes to the enhanced sensitivity to cocaine caused by nicotine exposure in young mice.

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Autores principales:	K. E. Linker, M. G. Elabd, P. Tawadrous, M. Cano, K. N. Green, M. A. Wood, F. M. Leslie
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/755bec2dfbc646cf85593a656efff149
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spelling	oai:doaj.org-article:755bec2dfbc646cf85593a656efff1492021-12-02T17:31:24ZMicroglial activation increases cocaine self-administration following adolescent nicotine exposure10.1038/s41467-019-14173-32041-1723https://doaj.org/article/755bec2dfbc646cf85593a656efff1492020-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-14173-3https://doaj.org/toc/2041-1723Adolescents are particularly sensitive to nicotine. Here the authors show that in mice, microglial activation contributes to the enhanced sensitivity to cocaine caused by nicotine exposure in young mice.K. E. LinkerM. G. ElabdP. TawadrousM. CanoK. N. GreenM. A. WoodF. M. LeslieNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q K. E. Linker M. G. Elabd P. Tawadrous M. Cano K. N. Green M. A. Wood F. M. Leslie Microglial activation increases cocaine self-administration following adolescent nicotine exposure
description	Adolescents are particularly sensitive to nicotine. Here the authors show that in mice, microglial activation contributes to the enhanced sensitivity to cocaine caused by nicotine exposure in young mice.
format	article
author	K. E. Linker M. G. Elabd P. Tawadrous M. Cano K. N. Green M. A. Wood F. M. Leslie
author_facet	K. E. Linker M. G. Elabd P. Tawadrous M. Cano K. N. Green M. A. Wood F. M. Leslie
author_sort	K. E. Linker
title	Microglial activation increases cocaine self-administration following adolescent nicotine exposure
title_short	Microglial activation increases cocaine self-administration following adolescent nicotine exposure
title_full	Microglial activation increases cocaine self-administration following adolescent nicotine exposure
title_fullStr	Microglial activation increases cocaine self-administration following adolescent nicotine exposure
title_full_unstemmed	Microglial activation increases cocaine self-administration following adolescent nicotine exposure
title_sort	microglial activation increases cocaine self-administration following adolescent nicotine exposure
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/755bec2dfbc646cf85593a656efff149
work_keys_str_mv	AT kelinker microglialactivationincreasescocaineselfadministrationfollowingadolescentnicotineexposure AT mgelabd microglialactivationincreasescocaineselfadministrationfollowingadolescentnicotineexposure AT ptawadrous microglialactivationincreasescocaineselfadministrationfollowingadolescentnicotineexposure AT mcano microglialactivationincreasescocaineselfadministrationfollowingadolescentnicotineexposure AT kngreen microglialactivationincreasescocaineselfadministrationfollowingadolescentnicotineexposure AT mawood microglialactivationincreasescocaineselfadministrationfollowingadolescentnicotineexposure AT fmleslie microglialactivationincreasescocaineselfadministrationfollowingadolescentnicotineexposure
_version_	1718380621478232064

Microglial activation increases cocaine self-administration following adolescent nicotine exposure

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