Management of gestational diabetes mellitus

Annunziata Lapolla, Maria Grazia Dalfr&agrave;, Domenico FedeleDepartment of Medical and Surgical Sciences, Padova University, ItalyAbstract: The incidence of gestational diabetes mellitus (GDM) is on the increase and, if not diagnosed, managed and treated adequately, can have unfavorable ma...

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Autores principales:	Annunziata Lapolla, Maria Grazia Dalfr&agrave;, Domenico Fedele
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2009
Materias:	Specialties of internal medicine RC581-951
Acceso en línea:	https://doaj.org/article/755d59defcb24749b5835bf51869dabe
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spelling	oai:doaj.org-article:755d59defcb24749b5835bf51869dabe2021-12-02T02:14:15ZManagement of gestational diabetes mellitus1178-7007https://doaj.org/article/755d59defcb24749b5835bf51869dabe2009-06-01T00:00:00Zhttp://www.dovepress.com/management-of-gestational-diabetes-mellitus-a3266https://doaj.org/toc/1178-7007Annunziata Lapolla, Maria Grazia Dalfr&agrave;, Domenico FedeleDepartment of Medical and Surgical Sciences, Padova University, ItalyAbstract: The incidence of gestational diabetes mellitus (GDM) is on the increase and, if not diagnosed, managed and treated adequately, can have unfavorable maternal and fetal outcomes. Several studies have shown that glycemic values considered as adequate in the past when monitoring GDM failed to contain these adverse outcomes and randomized trials are needed to ascertain whether these targets should be lowered. Dietary restrictions remain the mainstay of GDM management and suitable physical exercise can help too. The use of rapid-acting insulin analogues (lispro and aspart) are novel treatments for improving metabolic control by reducing postprandial glycemia, while long-acting insulin analogues need to be evaluated by further studies for safety in clinical use before they can be prescribed. Numerous studies have found glyburide and metformin safe in women with GDM but more randomized controlled trials are needed, with a long-term follow-up of mother and child, to confirm these results.Keywords: gestational diabetes, glucose management, obstetric management, maternal complications, fetal complications Annunziata LapollaMaria Grazia Dalfr&agrave;Domenico FedeleDove Medical PressarticleSpecialties of internal medicineRC581-951ENDiabetes, Metabolic Syndrome and Obesity: Targets and Therapy, Vol 2009, Iss default, Pp 73-82 (2009)
institution	DOAJ
collection	DOAJ
language	EN
topic	Specialties of internal medicine RC581-951
spellingShingle	Specialties of internal medicine RC581-951 Annunziata Lapolla Maria Grazia Dalfr&agrave; Domenico Fedele Management of gestational diabetes mellitus
description	Annunziata Lapolla, Maria Grazia Dalfr&agrave;, Domenico FedeleDepartment of Medical and Surgical Sciences, Padova University, ItalyAbstract: The incidence of gestational diabetes mellitus (GDM) is on the increase and, if not diagnosed, managed and treated adequately, can have unfavorable maternal and fetal outcomes. Several studies have shown that glycemic values considered as adequate in the past when monitoring GDM failed to contain these adverse outcomes and randomized trials are needed to ascertain whether these targets should be lowered. Dietary restrictions remain the mainstay of GDM management and suitable physical exercise can help too. The use of rapid-acting insulin analogues (lispro and aspart) are novel treatments for improving metabolic control by reducing postprandial glycemia, while long-acting insulin analogues need to be evaluated by further studies for safety in clinical use before they can be prescribed. Numerous studies have found glyburide and metformin safe in women with GDM but more randomized controlled trials are needed, with a long-term follow-up of mother and child, to confirm these results.Keywords: gestational diabetes, glucose management, obstetric management, maternal complications, fetal complications
format	article
author	Annunziata Lapolla Maria Grazia Dalfr&agrave; Domenico Fedele
author_facet	Annunziata Lapolla Maria Grazia Dalfr&agrave; Domenico Fedele
author_sort	Annunziata Lapolla
title	Management of gestational diabetes mellitus
title_short	Management of gestational diabetes mellitus
title_full	Management of gestational diabetes mellitus
title_fullStr	Management of gestational diabetes mellitus
title_full_unstemmed	Management of gestational diabetes mellitus
title_sort	management of gestational diabetes mellitus
publisher	Dove Medical Press
publishDate	2009
url	https://doaj.org/article/755d59defcb24749b5835bf51869dabe
work_keys_str_mv	AT annunziatalapolla managementofgestationaldiabetesmellitus AT mariagraziadalframpagrave managementofgestationaldiabetesmellitus AT domenicofedele managementofgestationaldiabetesmellitus
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Management of gestational diabetes mellitus

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