An Antibiotic-Impacted Microbiota Compromises the Development of Colonic Regulatory T Cells and Predisposes to Dysregulated Immune Responses

The assembly of microbial communities that populate all mucosal surfaces of the human body begins right after birth. This process is prone to disruption as newborns and young infants are increasingly exposed to antibiotics, both deliberately for therapeutic purposes, and as a consequence of transma...

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Autores principales: Xiaozhou Zhang, Timothy C. Borbet, Angela Fallegger, Matthew F. Wipperman, Martin J. Blaser, Anne Müller
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2021
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Acceso en línea:https://doaj.org/article/757ccd3d5b4b47a58b04bcab20999b82
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spelling oai:doaj.org-article:757ccd3d5b4b47a58b04bcab20999b822021-11-03T18:15:37ZAn Antibiotic-Impacted Microbiota Compromises the Development of Colonic Regulatory T Cells and Predisposes to Dysregulated Immune Responses2161-21292150-751110.1128/mBio.03335-20https://doaj.org/article/757ccd3d5b4b47a58b04bcab20999b822021-02-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mBio.03335-20https://doaj.org/toc/2161-2129https://doaj.org/toc/2150-7511 The assembly of microbial communities that populate all mucosal surfaces of the human body begins right after birth. This process is prone to disruption as newborns and young infants are increasingly exposed to antibiotics, both deliberately for therapeutic purposes, and as a consequence of transmaternal exposure.Xiaozhou ZhangTimothy C. BorbetAngela FalleggerMatthew F. WippermanMartin J. BlaserAnne MüllerAmerican Society for MicrobiologyarticleMicrobiologyQR1-502ENmBio, Vol 12, Iss 1 (2021)
institution DOAJ
collection DOAJ
language EN
topic Microbiology
QR1-502
spellingShingle Microbiology
QR1-502
Xiaozhou Zhang
Timothy C. Borbet
Angela Fallegger
Matthew F. Wipperman
Martin J. Blaser
Anne Müller
An Antibiotic-Impacted Microbiota Compromises the Development of Colonic Regulatory T Cells and Predisposes to Dysregulated Immune Responses
description The assembly of microbial communities that populate all mucosal surfaces of the human body begins right after birth. This process is prone to disruption as newborns and young infants are increasingly exposed to antibiotics, both deliberately for therapeutic purposes, and as a consequence of transmaternal exposure.
format article
author Xiaozhou Zhang
Timothy C. Borbet
Angela Fallegger
Matthew F. Wipperman
Martin J. Blaser
Anne Müller
author_facet Xiaozhou Zhang
Timothy C. Borbet
Angela Fallegger
Matthew F. Wipperman
Martin J. Blaser
Anne Müller
author_sort Xiaozhou Zhang
title An Antibiotic-Impacted Microbiota Compromises the Development of Colonic Regulatory T Cells and Predisposes to Dysregulated Immune Responses
title_short An Antibiotic-Impacted Microbiota Compromises the Development of Colonic Regulatory T Cells and Predisposes to Dysregulated Immune Responses
title_full An Antibiotic-Impacted Microbiota Compromises the Development of Colonic Regulatory T Cells and Predisposes to Dysregulated Immune Responses
title_fullStr An Antibiotic-Impacted Microbiota Compromises the Development of Colonic Regulatory T Cells and Predisposes to Dysregulated Immune Responses
title_full_unstemmed An Antibiotic-Impacted Microbiota Compromises the Development of Colonic Regulatory T Cells and Predisposes to Dysregulated Immune Responses
title_sort antibiotic-impacted microbiota compromises the development of colonic regulatory t cells and predisposes to dysregulated immune responses
publisher American Society for Microbiology
publishDate 2021
url https://doaj.org/article/757ccd3d5b4b47a58b04bcab20999b82
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