The Cep57-pericentrin module organizes PCM expansion and centriole engagement

Centriole disengagement occurs towards mitotic exit and involves cleavage of pericentrin, a component of the pericentriolar material. Here the authors show that depletion of the centrosomal protein Cep57 leads to precocious centriole disengagement, and that Cep57 binds pericentrin.

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Autores principales:	Koki Watanabe, Daisuke Takao, Kei K Ito, Mikiko Takahashi, Daiju Kitagawa
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/759774e53a804a65b6bc1ac46668a329
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id	oai:doaj.org-article:759774e53a804a65b6bc1ac46668a329
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spelling	oai:doaj.org-article:759774e53a804a65b6bc1ac46668a3292021-12-02T15:35:32ZThe Cep57-pericentrin module organizes PCM expansion and centriole engagement10.1038/s41467-019-08862-22041-1723https://doaj.org/article/759774e53a804a65b6bc1ac46668a3292019-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-08862-2https://doaj.org/toc/2041-1723Centriole disengagement occurs towards mitotic exit and involves cleavage of pericentrin, a component of the pericentriolar material. Here the authors show that depletion of the centrosomal protein Cep57 leads to precocious centriole disengagement, and that Cep57 binds pericentrin.Koki WatanabeDaisuke TakaoKei K ItoMikiko TakahashiDaiju KitagawaNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Koki Watanabe Daisuke Takao Kei K Ito Mikiko Takahashi Daiju Kitagawa The Cep57-pericentrin module organizes PCM expansion and centriole engagement
description	Centriole disengagement occurs towards mitotic exit and involves cleavage of pericentrin, a component of the pericentriolar material. Here the authors show that depletion of the centrosomal protein Cep57 leads to precocious centriole disengagement, and that Cep57 binds pericentrin.
format	article
author	Koki Watanabe Daisuke Takao Kei K Ito Mikiko Takahashi Daiju Kitagawa
author_facet	Koki Watanabe Daisuke Takao Kei K Ito Mikiko Takahashi Daiju Kitagawa
author_sort	Koki Watanabe
title	The Cep57-pericentrin module organizes PCM expansion and centriole engagement
title_short	The Cep57-pericentrin module organizes PCM expansion and centriole engagement
title_full	The Cep57-pericentrin module organizes PCM expansion and centriole engagement
title_fullStr	The Cep57-pericentrin module organizes PCM expansion and centriole engagement
title_full_unstemmed	The Cep57-pericentrin module organizes PCM expansion and centriole engagement
title_sort	cep57-pericentrin module organizes pcm expansion and centriole engagement
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/759774e53a804a65b6bc1ac46668a329
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The Cep57-pericentrin module organizes PCM expansion and centriole engagement

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