The Cep57-pericentrin module organizes PCM expansion and centriole engagement
Centriole disengagement occurs towards mitotic exit and involves cleavage of pericentrin, a component of the pericentriolar material. Here the authors show that depletion of the centrosomal protein Cep57 leads to precocious centriole disengagement, and that Cep57 binds pericentrin.
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Autores principales: | Koki Watanabe, Daisuke Takao, Kei K Ito, Mikiko Takahashi, Daiju Kitagawa |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2019
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Materias: | |
Acceso en línea: | https://doaj.org/article/759774e53a804a65b6bc1ac46668a329 |
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