Evidence of Hearing Loss and Unrelated Toxoplasmosis in a Free-Ranging Harbour Porpoise (<i>Phocoena phocoena</i>)

Evidence of hearing impairment was identified in a harbour porpoise (<i>Phocoena phocoena</i>) on the basis of scanning electron microscopy. In addition, based on histopathology and immunohistochemistry, there were signs of unrelated cerebral toxoplasmosis. The six-year old individual li...

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Autores principales:	Maria Morell, Lonneke L. IJsseldijk, Alinda J. Berends, Andrea Gröne, Ursula Siebert, Stephen A. Raverty, Robert E. Shadwick, Marja J. L. Kik
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	<i>Toxoplasma gondii</i> North Sea live stranding post-mortem examination encephalitis noise-induced hearing loss Veterinary medicine SF600-1100 Zoology QL1-991
Acceso en línea:	https://doaj.org/article/759c3675b9fa42d98752ff5fef6c4f98
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spelling	oai:doaj.org-article:759c3675b9fa42d98752ff5fef6c4f982021-11-25T16:14:16ZEvidence of Hearing Loss and Unrelated Toxoplasmosis in a Free-Ranging Harbour Porpoise (<i>Phocoena phocoena</i>)10.3390/ani111130582076-2615https://doaj.org/article/759c3675b9fa42d98752ff5fef6c4f982021-10-01T00:00:00Zhttps://www.mdpi.com/2076-2615/11/11/3058https://doaj.org/toc/2076-2615Evidence of hearing impairment was identified in a harbour porpoise (<i>Phocoena phocoena</i>) on the basis of scanning electron microscopy. In addition, based on histopathology and immunohistochemistry, there were signs of unrelated cerebral toxoplasmosis. The six-year old individual live stranded on the Dutch coast at Domburg in 2016 and died a few hours later. The most significant gross lesion was multifocal necrosis and haemorrhage of the cerebrum. Histopathology of the brain revealed extensive necrosis and haemorrhage in the cerebrum with multifocal accumulations of degenerated neutrophils, lymphocytes and macrophages, and perivascular lymphocytic cuffing. The diagnosis of cerebral toxoplasmosis was confirmed by positive staining of protozoa with anti-<i>Toxoplasma gondii</i> antibodies. Tachyzoites were not observed histologically in any of the examined tissues. Ultrastructural evaluation of the inner ear revealed evidence of scattered loss of outer hair cells in a 290 µm long segment of the apical turn of the cochlea, and in a focal region of ~ 1.5 mm from the apex of the cochlea, which was compatible with noise-induced hearing loss. This is the first case of concurrent presumptive noise-induced hearing loss and toxoplasmosis in a free-ranging harbour porpoise from the North Sea.Maria MorellLonneke L. IJsseldijkAlinda J. BerendsAndrea GröneUrsula SiebertStephen A. RavertyRobert E. ShadwickMarja J. L. KikMDPI AGarticle<i>Toxoplasma gondii</i>North Sealive strandingpost-mortem examinationencephalitisnoise-induced hearing lossVeterinary medicineSF600-1100ZoologyQL1-991ENAnimals, Vol 11, Iss 3058, p 3058 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	<i>Toxoplasma gondii</i> North Sea live stranding post-mortem examination encephalitis noise-induced hearing loss Veterinary medicine SF600-1100 Zoology QL1-991
spellingShingle	<i>Toxoplasma gondii</i> North Sea live stranding post-mortem examination encephalitis noise-induced hearing loss Veterinary medicine SF600-1100 Zoology QL1-991 Maria Morell Lonneke L. IJsseldijk Alinda J. Berends Andrea Gröne Ursula Siebert Stephen A. Raverty Robert E. Shadwick Marja J. L. Kik Evidence of Hearing Loss and Unrelated Toxoplasmosis in a Free-Ranging Harbour Porpoise (<i>Phocoena phocoena</i>)
description	Evidence of hearing impairment was identified in a harbour porpoise (<i>Phocoena phocoena</i>) on the basis of scanning electron microscopy. In addition, based on histopathology and immunohistochemistry, there were signs of unrelated cerebral toxoplasmosis. The six-year old individual live stranded on the Dutch coast at Domburg in 2016 and died a few hours later. The most significant gross lesion was multifocal necrosis and haemorrhage of the cerebrum. Histopathology of the brain revealed extensive necrosis and haemorrhage in the cerebrum with multifocal accumulations of degenerated neutrophils, lymphocytes and macrophages, and perivascular lymphocytic cuffing. The diagnosis of cerebral toxoplasmosis was confirmed by positive staining of protozoa with anti-<i>Toxoplasma gondii</i> antibodies. Tachyzoites were not observed histologically in any of the examined tissues. Ultrastructural evaluation of the inner ear revealed evidence of scattered loss of outer hair cells in a 290 µm long segment of the apical turn of the cochlea, and in a focal region of ~ 1.5 mm from the apex of the cochlea, which was compatible with noise-induced hearing loss. This is the first case of concurrent presumptive noise-induced hearing loss and toxoplasmosis in a free-ranging harbour porpoise from the North Sea.
format	article
author	Maria Morell Lonneke L. IJsseldijk Alinda J. Berends Andrea Gröne Ursula Siebert Stephen A. Raverty Robert E. Shadwick Marja J. L. Kik
author_facet	Maria Morell Lonneke L. IJsseldijk Alinda J. Berends Andrea Gröne Ursula Siebert Stephen A. Raverty Robert E. Shadwick Marja J. L. Kik
author_sort	Maria Morell
title	Evidence of Hearing Loss and Unrelated Toxoplasmosis in a Free-Ranging Harbour Porpoise (<i>Phocoena phocoena</i>)
title_short	Evidence of Hearing Loss and Unrelated Toxoplasmosis in a Free-Ranging Harbour Porpoise (<i>Phocoena phocoena</i>)
title_full	Evidence of Hearing Loss and Unrelated Toxoplasmosis in a Free-Ranging Harbour Porpoise (<i>Phocoena phocoena</i>)
title_fullStr	Evidence of Hearing Loss and Unrelated Toxoplasmosis in a Free-Ranging Harbour Porpoise (<i>Phocoena phocoena</i>)
title_full_unstemmed	Evidence of Hearing Loss and Unrelated Toxoplasmosis in a Free-Ranging Harbour Porpoise (<i>Phocoena phocoena</i>)
title_sort	evidence of hearing loss and unrelated toxoplasmosis in a free-ranging harbour porpoise (<i>phocoena phocoena</i>)
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/759c3675b9fa42d98752ff5fef6c4f98
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Evidence of Hearing Loss and Unrelated Toxoplasmosis in a Free-Ranging Harbour Porpoise (<i>Phocoena phocoena</i>)

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