Genetically-defined deficiency of mannose-binding lectin is associated with protection after experimental stroke in mice and outcome in human stroke.

Genetically-defined deficiency of mannose-binding lectin is associated with protection after experimental stroke in mice and outcome in human stroke.

<h4>Background</h4>The complement system is a major effector of innate immunity that has been involved in stroke brain damage. Complement activation occurs through the classical, alternative and lectin pathways. The latter is initiated by mannose-binding lectin (MBL) and MBL-associated s...

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Autores principales: Alvaro Cervera, Anna M Planas, Carles Justicia, Xabier Urra, Jens C Jensenius, Ferran Torres, Francisco Lozano, Angel Chamorro
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2010
Materias:
Medicine
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Science
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Acceso en línea:https://doaj.org/article/75a92e0934394587a0d82e3a35f0296a
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