A region within the third extracellular loop of rat Aquaporin 6 precludes trafficking to plasma membrane in a heterologous cell line

Abstract The inability to over-express Aquaporin 6 (AQP6) in the plasma membrane of heterologous cells has hampered efforts to further characterize the function of this aquaglyceroporin membrane protein at atomic detail using crystallographic approaches. Using an Aquaporin 3-tGFP Reporter (AGR) syst...

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Autores principales: D. C. Soler, T. Kowatz, A. E. Sloan, T. S. McCormick, K. D. Cooper, R. Stepanyan, A. Engel, A. Vahedi-Faridi
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/75ba498787aa4de3baf4ebb95d66607f
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