TLR4 signalling via Piezo1 engages and enhances the macrophage mediated host response during bacterial infection

Innate immune cells respond to a number of environmental cues including TLR signalling. Here the authors implicate mechanical sensor Piezo1 in the TLR4 mediated host response to bacterial infection and implicate it in the enhancement of macrophage mediated host response.

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Autores principales:	Jing Geng, Yiran Shi, Jinjia Zhang, Bingying Yang, Ping Wang, Weihong Yuan, Hao Zhao, Junhong Li, Funiu Qin, Lixin Hong, Changchuan Xie, Xianming Deng, Yujie Sun, Congying Wu, Lanfen Chen, Dawang Zhou
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/75c48bfb0aaf48df8cd5e8d33bcbb665
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

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spelling	oai:doaj.org-article:75c48bfb0aaf48df8cd5e8d33bcbb6652021-12-02T17:38:25ZTLR4 signalling via Piezo1 engages and enhances the macrophage mediated host response during bacterial infection10.1038/s41467-021-23683-y2041-1723https://doaj.org/article/75c48bfb0aaf48df8cd5e8d33bcbb6652021-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23683-yhttps://doaj.org/toc/2041-1723Innate immune cells respond to a number of environmental cues including TLR signalling. Here the authors implicate mechanical sensor Piezo1 in the TLR4 mediated host response to bacterial infection and implicate it in the enhancement of macrophage mediated host response.Jing GengYiran ShiJinjia ZhangBingying YangPing WangWeihong YuanHao ZhaoJunhong LiFuniu QinLixin HongChangchuan XieXianming DengYujie SunCongying WuLanfen ChenDawang ZhouNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Jing Geng Yiran Shi Jinjia Zhang Bingying Yang Ping Wang Weihong Yuan Hao Zhao Junhong Li Funiu Qin Lixin Hong Changchuan Xie Xianming Deng Yujie Sun Congying Wu Lanfen Chen Dawang Zhou TLR4 signalling via Piezo1 engages and enhances the macrophage mediated host response during bacterial infection
description	Innate immune cells respond to a number of environmental cues including TLR signalling. Here the authors implicate mechanical sensor Piezo1 in the TLR4 mediated host response to bacterial infection and implicate it in the enhancement of macrophage mediated host response.
format	article
author	Jing Geng Yiran Shi Jinjia Zhang Bingying Yang Ping Wang Weihong Yuan Hao Zhao Junhong Li Funiu Qin Lixin Hong Changchuan Xie Xianming Deng Yujie Sun Congying Wu Lanfen Chen Dawang Zhou
author_facet	Jing Geng Yiran Shi Jinjia Zhang Bingying Yang Ping Wang Weihong Yuan Hao Zhao Junhong Li Funiu Qin Lixin Hong Changchuan Xie Xianming Deng Yujie Sun Congying Wu Lanfen Chen Dawang Zhou
author_sort	Jing Geng
title	TLR4 signalling via Piezo1 engages and enhances the macrophage mediated host response during bacterial infection
title_short	TLR4 signalling via Piezo1 engages and enhances the macrophage mediated host response during bacterial infection
title_full	TLR4 signalling via Piezo1 engages and enhances the macrophage mediated host response during bacterial infection
title_fullStr	TLR4 signalling via Piezo1 engages and enhances the macrophage mediated host response during bacterial infection
title_full_unstemmed	TLR4 signalling via Piezo1 engages and enhances the macrophage mediated host response during bacterial infection
title_sort	tlr4 signalling via piezo1 engages and enhances the macrophage mediated host response during bacterial infection
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/75c48bfb0aaf48df8cd5e8d33bcbb665
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TLR4 signalling via Piezo1 engages and enhances the macrophage mediated host response during bacterial infection

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