Scalable total synthesis and comprehensive structure–activity relationship studies of the phytotoxin coronatine

Development of comprehensive structure–activity relationships for coronatine has been a major goal in the agrochemical industry. Here, the authors report the gram-scale production and structure–activity relationship of parent coronafacic acid and ultimately rationalise the biological activity of ana...

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Main Authors:	Mairi M. Littleson, Christopher M. Baker, Anne J. Dalençon, Elizabeth C. Frye, Craig Jamieson, Alan R. Kennedy, Kenneth B. Ling, Matthew M. McLachlan, Mark G. Montgomery, Claire J. Russell, Allan J. B. Watson
Format:	article
Language:	EN
Published:	Nature Portfolio 2018
Subjects:	Science Q
Online Access:	https://doaj.org/article/75c58f1cf7984677b6fa1c5db1fec3b8
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spelling	oai:doaj.org-article:75c58f1cf7984677b6fa1c5db1fec3b82021-12-02T17:32:49ZScalable total synthesis and comprehensive structure–activity relationship studies of the phytotoxin coronatine10.1038/s41467-018-03443-12041-1723https://doaj.org/article/75c58f1cf7984677b6fa1c5db1fec3b82018-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03443-1https://doaj.org/toc/2041-1723Development of comprehensive structure–activity relationships for coronatine has been a major goal in the agrochemical industry. Here, the authors report the gram-scale production and structure–activity relationship of parent coronafacic acid and ultimately rationalise the biological activity of analogues of this phytotoxin.Mairi M. LittlesonChristopher M. BakerAnne J. DalençonElizabeth C. FryeCraig JamiesonAlan R. KennedyKenneth B. LingMatthew M. McLachlanMark G. MontgomeryClaire J. RussellAllan J. B. WatsonNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Mairi M. Littleson Christopher M. Baker Anne J. Dalençon Elizabeth C. Frye Craig Jamieson Alan R. Kennedy Kenneth B. Ling Matthew M. McLachlan Mark G. Montgomery Claire J. Russell Allan J. B. Watson Scalable total synthesis and comprehensive structure–activity relationship studies of the phytotoxin coronatine
description	Development of comprehensive structure–activity relationships for coronatine has been a major goal in the agrochemical industry. Here, the authors report the gram-scale production and structure–activity relationship of parent coronafacic acid and ultimately rationalise the biological activity of analogues of this phytotoxin.
format	article
author	Mairi M. Littleson Christopher M. Baker Anne J. Dalençon Elizabeth C. Frye Craig Jamieson Alan R. Kennedy Kenneth B. Ling Matthew M. McLachlan Mark G. Montgomery Claire J. Russell Allan J. B. Watson
author_facet	Mairi M. Littleson Christopher M. Baker Anne J. Dalençon Elizabeth C. Frye Craig Jamieson Alan R. Kennedy Kenneth B. Ling Matthew M. McLachlan Mark G. Montgomery Claire J. Russell Allan J. B. Watson
author_sort	Mairi M. Littleson
title	Scalable total synthesis and comprehensive structure–activity relationship studies of the phytotoxin coronatine
title_short	Scalable total synthesis and comprehensive structure–activity relationship studies of the phytotoxin coronatine
title_full	Scalable total synthesis and comprehensive structure–activity relationship studies of the phytotoxin coronatine
title_fullStr	Scalable total synthesis and comprehensive structure–activity relationship studies of the phytotoxin coronatine
title_full_unstemmed	Scalable total synthesis and comprehensive structure–activity relationship studies of the phytotoxin coronatine
title_sort	scalable total synthesis and comprehensive structure–activity relationship studies of the phytotoxin coronatine
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/75c58f1cf7984677b6fa1c5db1fec3b8
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Scalable total synthesis and comprehensive structure–activity relationship studies of the phytotoxin coronatine

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