Specific inhibition of FGF5-induced cell proliferation by RNA aptamers

Specific inhibition of FGF5-induced cell proliferation by RNA aptamers

Abstract Fibroblast growth factor 5 (FGF5) is a crucial regulator of hair growth and an oncogenic factor in several human cancers. To generate FGF5 inhibitors, we performed Systematic Evolution of Ligands by EXponential enrichment and obtained novel RNA aptamers that have high affinity to human FGF5...

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Autores principales: Ryo Amano, Masato Namekata, Masataka Horiuchi, Minami Saso, Takuya Yanagisawa, Yoichiro Tanaka, Farhana Ishrat Ghani, Masakuni Yamamoto, Taiichi Sakamoto
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/75c971d601c64b4c9394e84857b8cf47
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