Recognition of non-CpG repeats in Alu and ribosomal RNAs by the Z-RNA binding domain of ADAR1 induces A-Z junctions

ADAR1 is an interferon-induced enzyme that catalyzes editing of adenine to inosine across the transcriptome as part of the immune response. Here the authors establish how ADAR1 recognizes non-CpG RNA sequences to facilitate the formation of A-Z junctions.

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Autores principales:	Parker J. Nichols, Shaun Bevers, Morkos Henen, Jeffrey S. Kieft, Quentin Vicens, Beat Vögeli
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/75d14e461d4e48f38695886425928e67
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spelling	oai:doaj.org-article:75d14e461d4e48f38695886425928e672021-12-02T10:44:18ZRecognition of non-CpG repeats in Alu and ribosomal RNAs by the Z-RNA binding domain of ADAR1 induces A-Z junctions10.1038/s41467-021-21039-02041-1723https://doaj.org/article/75d14e461d4e48f38695886425928e672021-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21039-0https://doaj.org/toc/2041-1723ADAR1 is an interferon-induced enzyme that catalyzes editing of adenine to inosine across the transcriptome as part of the immune response. Here the authors establish how ADAR1 recognizes non-CpG RNA sequences to facilitate the formation of A-Z junctions.Parker J. NicholsShaun BeversMorkos HenenJeffrey S. KieftQuentin VicensBeat VögeliNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Parker J. Nichols Shaun Bevers Morkos Henen Jeffrey S. Kieft Quentin Vicens Beat Vögeli Recognition of non-CpG repeats in Alu and ribosomal RNAs by the Z-RNA binding domain of ADAR1 induces A-Z junctions
description	ADAR1 is an interferon-induced enzyme that catalyzes editing of adenine to inosine across the transcriptome as part of the immune response. Here the authors establish how ADAR1 recognizes non-CpG RNA sequences to facilitate the formation of A-Z junctions.
format	article
author	Parker J. Nichols Shaun Bevers Morkos Henen Jeffrey S. Kieft Quentin Vicens Beat Vögeli
author_facet	Parker J. Nichols Shaun Bevers Morkos Henen Jeffrey S. Kieft Quentin Vicens Beat Vögeli
author_sort	Parker J. Nichols
title	Recognition of non-CpG repeats in Alu and ribosomal RNAs by the Z-RNA binding domain of ADAR1 induces A-Z junctions
title_short	Recognition of non-CpG repeats in Alu and ribosomal RNAs by the Z-RNA binding domain of ADAR1 induces A-Z junctions
title_full	Recognition of non-CpG repeats in Alu and ribosomal RNAs by the Z-RNA binding domain of ADAR1 induces A-Z junctions
title_fullStr	Recognition of non-CpG repeats in Alu and ribosomal RNAs by the Z-RNA binding domain of ADAR1 induces A-Z junctions
title_full_unstemmed	Recognition of non-CpG repeats in Alu and ribosomal RNAs by the Z-RNA binding domain of ADAR1 induces A-Z junctions
title_sort	recognition of non-cpg repeats in alu and ribosomal rnas by the z-rna binding domain of adar1 induces a-z junctions
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/75d14e461d4e48f38695886425928e67
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Recognition of non-CpG repeats in Alu and ribosomal RNAs by the Z-RNA binding domain of ADAR1 induces A-Z junctions

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