Type-3 Hyaluronan Synthase Attenuates Tumor Cells Invasion in Human Mammary Parenchymal Tissues

Type-3 Hyaluronan Synthase Attenuates Tumor Cells Invasion in Human Mammary Parenchymal Tissues

The microenvironment for tumor growth and developing metastasis should be essential. This study demonstrated that the hyaluronic acid synthase 3 (HAS3) protein and its enzymatic product hyaluronic acid (HA) encompassed in the subcutaneous extracellular matrix can attenuate the invasion of human brea...

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Bibliographic Details
Main Authors: Wen-Jui Lee, Shih-Hsin Tu, Tzu-Chun Cheng, Juo-Han Lin, Ming-Thau Sheu, Ching-Chuan Kuo, Chun A. Changou, Chih-Hsiung Wu, Hui-Wen Chang, Hang-Lung Chang, Li-Ching Chen, Yuan-Soon Ho
Format: article
Language:EN
Published: MDPI AG 2021
Subjects:
breast cancer
tumor microenvironment
hyaluronan synthase 3
tubulin acetylation
autophagy
Organic chemistry
QD241-441
Online Access:https://doaj.org/article/75da9fb660f848f9a5d1943f57c0c831
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https://doaj.org/article/75da9fb660f848f9a5d1943f57c0c831

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