Behind Traditional Semi-quantitative Scores of Myocardial Perfusion Imaging: An Eye on Niche Parameters

The evaluation of stress-induced myocardial perfusion defects by non-invasive myocardial perfusion imaging (MPI) modalities has a leading role in the identification of coronary artery disease, and has excellent diagnostic and prognostic value. Non-invasive MPI can be performed using conventional and...

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Autores principales:	Carmela Nappi, Valeria Gaudieri, Alberto Cuocolo
Formato:	article
Lenguaje:	EN
Publicado:	Radcliffe Medical Media 2019
Materias:	Diseases of the circulatory (Cardiovascular) system RC666-701
Acceso en línea:	https://doaj.org/article/75e2da3728ef4139b4139d9b4c5336cc
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spelling	oai:doaj.org-article:75e2da3728ef4139b4139d9b4c5336cc2021-12-04T16:01:19ZBehind Traditional Semi-quantitative Scores of Myocardial Perfusion Imaging: An Eye on Niche Parameters10.15420/ecr.2019.5.11758-37641758-3756https://doaj.org/article/75e2da3728ef4139b4139d9b4c5336cc2019-01-01T00:00:00Zhttps://www.ecrjournal.com/articles/behind-traditional-semi-quantitative-scores-myocardial-perfusion-imaging-eye-nichehttps://doaj.org/toc/1758-3756https://doaj.org/toc/1758-3764The evaluation of stress-induced myocardial perfusion defects by non-invasive myocardial perfusion imaging (MPI) modalities has a leading role in the identification of coronary artery disease, and has excellent diagnostic and prognostic value. Non-invasive MPI can be performed using conventional and novel gamma cameras or by PET/CT. New software has allowed novel parameters that may have a role in the identification of early marks of cardiac impairment to be evaluated. We aim to give an overview of niche parameters obtainable by single photon emission CT (SPECT) and PET/CT MPI that may help practitioners to detect initial signs of cardiac damage and identify new therapy targets. In particular, we summarise the role of left ventricular geometry indices for remodelling, phase analysis parameters to evaluate mechanical dyssynchrony, the concept of relative flow reserve in the evaluation of flow-limiting epicardial stenosis, vascular age and epicardial adipose tissue as early markers of atherosclerotic burden, and emerging parameters for the evaluation of myocardial innervation, such as the total defect score.Carmela NappiValeria GaudieriAlberto CuocoloRadcliffe Medical MediaarticleDiseases of the circulatory (Cardiovascular) systemRC666-701ENEuropean Cardiology Review , Vol 14, Iss 1, Pp 13-17 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Diseases of the circulatory (Cardiovascular) system RC666-701
spellingShingle	Diseases of the circulatory (Cardiovascular) system RC666-701 Carmela Nappi Valeria Gaudieri Alberto Cuocolo Behind Traditional Semi-quantitative Scores of Myocardial Perfusion Imaging: An Eye on Niche Parameters
description	The evaluation of stress-induced myocardial perfusion defects by non-invasive myocardial perfusion imaging (MPI) modalities has a leading role in the identification of coronary artery disease, and has excellent diagnostic and prognostic value. Non-invasive MPI can be performed using conventional and novel gamma cameras or by PET/CT. New software has allowed novel parameters that may have a role in the identification of early marks of cardiac impairment to be evaluated. We aim to give an overview of niche parameters obtainable by single photon emission CT (SPECT) and PET/CT MPI that may help practitioners to detect initial signs of cardiac damage and identify new therapy targets. In particular, we summarise the role of left ventricular geometry indices for remodelling, phase analysis parameters to evaluate mechanical dyssynchrony, the concept of relative flow reserve in the evaluation of flow-limiting epicardial stenosis, vascular age and epicardial adipose tissue as early markers of atherosclerotic burden, and emerging parameters for the evaluation of myocardial innervation, such as the total defect score.
format	article
author	Carmela Nappi Valeria Gaudieri Alberto Cuocolo
author_facet	Carmela Nappi Valeria Gaudieri Alberto Cuocolo
author_sort	Carmela Nappi
title	Behind Traditional Semi-quantitative Scores of Myocardial Perfusion Imaging: An Eye on Niche Parameters
title_short	Behind Traditional Semi-quantitative Scores of Myocardial Perfusion Imaging: An Eye on Niche Parameters
title_full	Behind Traditional Semi-quantitative Scores of Myocardial Perfusion Imaging: An Eye on Niche Parameters
title_fullStr	Behind Traditional Semi-quantitative Scores of Myocardial Perfusion Imaging: An Eye on Niche Parameters
title_full_unstemmed	Behind Traditional Semi-quantitative Scores of Myocardial Perfusion Imaging: An Eye on Niche Parameters
title_sort	behind traditional semi-quantitative scores of myocardial perfusion imaging: an eye on niche parameters
publisher	Radcliffe Medical Media
publishDate	2019
url	https://doaj.org/article/75e2da3728ef4139b4139d9b4c5336cc
work_keys_str_mv	AT carmelanappi behindtraditionalsemiquantitativescoresofmyocardialperfusionimaginganeyeonnicheparameters AT valeriagaudieri behindtraditionalsemiquantitativescoresofmyocardialperfusionimaginganeyeonnicheparameters AT albertocuocolo behindtraditionalsemiquantitativescoresofmyocardialperfusionimaginganeyeonnicheparameters
_version_	1718372801730052096

Behind Traditional Semi-quantitative Scores of Myocardial Perfusion Imaging: An Eye on Niche Parameters

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