PDL2+ CD11b+ dermal dendritic cells capture topical antigen through hair follicles to prime LAP+ Tregs

Antigen present and presented in the structures of the skin can result in immune responses that elicit tolerance, protective immunity or allergy, depending on the immunological context. Here the authors describe a key role for the hair follicle and CD11b+ dendritic cells in the priming of local anti...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Leticia Tordesillas, Daniel Lozano-Ojalvo, David Dunkin, Lucie Mondoulet, Judith Agudo, Miriam Merad, Hugh A. Sampson, M. Cecilia Berin
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/75ed4751d3fc4cb1907b6e718589c93a
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:75ed4751d3fc4cb1907b6e718589c93a
record_format	dspace
spelling	oai:doaj.org-article:75ed4751d3fc4cb1907b6e718589c93a2021-12-02T16:50:11ZPDL2+ CD11b+ dermal dendritic cells capture topical antigen through hair follicles to prime LAP+ Tregs10.1038/s41467-018-07716-72041-1723https://doaj.org/article/75ed4751d3fc4cb1907b6e718589c93a2018-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07716-7https://doaj.org/toc/2041-1723Antigen present and presented in the structures of the skin can result in immune responses that elicit tolerance, protective immunity or allergy, depending on the immunological context. Here the authors describe a key role for the hair follicle and CD11b+ dendritic cells in the priming of local antigenic tolerance.Leticia TordesillasDaniel Lozano-OjalvoDavid DunkinLucie MondouletJudith AgudoMiriam MeradHugh A. SampsonM. Cecilia BerinNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Leticia Tordesillas Daniel Lozano-Ojalvo David Dunkin Lucie Mondoulet Judith Agudo Miriam Merad Hugh A. Sampson M. Cecilia Berin PDL2+ CD11b+ dermal dendritic cells capture topical antigen through hair follicles to prime LAP+ Tregs
description	Antigen present and presented in the structures of the skin can result in immune responses that elicit tolerance, protective immunity or allergy, depending on the immunological context. Here the authors describe a key role for the hair follicle and CD11b+ dendritic cells in the priming of local antigenic tolerance.
format	article
author	Leticia Tordesillas Daniel Lozano-Ojalvo David Dunkin Lucie Mondoulet Judith Agudo Miriam Merad Hugh A. Sampson M. Cecilia Berin
author_facet	Leticia Tordesillas Daniel Lozano-Ojalvo David Dunkin Lucie Mondoulet Judith Agudo Miriam Merad Hugh A. Sampson M. Cecilia Berin
author_sort	Leticia Tordesillas
title	PDL2+ CD11b+ dermal dendritic cells capture topical antigen through hair follicles to prime LAP+ Tregs
title_short	PDL2+ CD11b+ dermal dendritic cells capture topical antigen through hair follicles to prime LAP+ Tregs
title_full	PDL2+ CD11b+ dermal dendritic cells capture topical antigen through hair follicles to prime LAP+ Tregs
title_fullStr	PDL2+ CD11b+ dermal dendritic cells capture topical antigen through hair follicles to prime LAP+ Tregs
title_full_unstemmed	PDL2+ CD11b+ dermal dendritic cells capture topical antigen through hair follicles to prime LAP+ Tregs
title_sort	pdl2+ cd11b+ dermal dendritic cells capture topical antigen through hair follicles to prime lap+ tregs
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/75ed4751d3fc4cb1907b6e718589c93a
work_keys_str_mv	AT leticiatordesillas pdl2cd11bdermaldendriticcellscapturetopicalantigenthroughhairfolliclestoprimelaptregs AT daniellozanoojalvo pdl2cd11bdermaldendriticcellscapturetopicalantigenthroughhairfolliclestoprimelaptregs AT daviddunkin pdl2cd11bdermaldendriticcellscapturetopicalantigenthroughhairfolliclestoprimelaptregs AT luciemondoulet pdl2cd11bdermaldendriticcellscapturetopicalantigenthroughhairfolliclestoprimelaptregs AT judithagudo pdl2cd11bdermaldendriticcellscapturetopicalantigenthroughhairfolliclestoprimelaptregs AT miriammerad pdl2cd11bdermaldendriticcellscapturetopicalantigenthroughhairfolliclestoprimelaptregs AT hughasampson pdl2cd11bdermaldendriticcellscapturetopicalantigenthroughhairfolliclestoprimelaptregs AT mceciliaberin pdl2cd11bdermaldendriticcellscapturetopicalantigenthroughhairfolliclestoprimelaptregs
_version_	1718383106014052352

PDL2+ CD11b+ dermal dendritic cells capture topical antigen through hair follicles to prime LAP+ Tregs

Ejemplares similares