Differential p16 expression levels in the liver, hepatocytes and hepatocellular cell lines

Background One of the most frequently deleted genes in cancer is CDKN2A encoding p16. This protein is often overexpressed in senescent cells, while its suppression can bypass the oncogene-induced senescence to enable transformation and tumorigenesis. The roles of the protein p16 are recently being e...

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Autores principales: Barbara Kramar, Dušan Šuput, Irina Milisav
Formato: article
Lenguaje:EN
Publicado: PeerJ Inc. 2021
Materias:
p16
FaO
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Acceso en línea:https://doaj.org/article/761dfcb95a51440793c3a9df063a1ddb
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