Periprostatic adipocytes act as a driving force for prostate cancer progression in obesity
Obesity is associated with an elevated risk of prostate cancer. Here, the authors show that periprostatic adipose tissue promotes the migration and local invasion of prostate cancer cells by secreting the chemokine, CCL7, and that this process is enhanced in the context of obesity.
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| Lenguaje: | EN |
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Nature Portfolio
2016
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| Acceso en línea: | https://doaj.org/article/76341f57a9a14a39a266074f59420b55 |
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oai:doaj.org-article:76341f57a9a14a39a266074f59420b552021-12-02T15:34:56ZPeriprostatic adipocytes act as a driving force for prostate cancer progression in obesity10.1038/ncomms102302041-1723https://doaj.org/article/76341f57a9a14a39a266074f59420b552016-01-01T00:00:00Zhttps://doi.org/10.1038/ncomms10230https://doaj.org/toc/2041-1723Obesity is associated with an elevated risk of prostate cancer. Here, the authors show that periprostatic adipose tissue promotes the migration and local invasion of prostate cancer cells by secreting the chemokine, CCL7, and that this process is enhanced in the context of obesity.Victor LaurentAdrien GuérardCatherine MazerollesSophie Le GonidecAurélie TouletLaurence NietoFalek ZaidiBilal MajedDavid GarandeauYouri SocrierMuriel GolzioThomas CadoudalKarima ChaouiCedric DrayBernard MonsarratOdile SchiltzYuan Yuan WangBettina CoudercPhilippe ValetBernard MalavaudCatherine MullerNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-15 (2016) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Science Q |
| spellingShingle |
Science Q Victor Laurent Adrien Guérard Catherine Mazerolles Sophie Le Gonidec Aurélie Toulet Laurence Nieto Falek Zaidi Bilal Majed David Garandeau Youri Socrier Muriel Golzio Thomas Cadoudal Karima Chaoui Cedric Dray Bernard Monsarrat Odile Schiltz Yuan Yuan Wang Bettina Couderc Philippe Valet Bernard Malavaud Catherine Muller Periprostatic adipocytes act as a driving force for prostate cancer progression in obesity |
| description |
Obesity is associated with an elevated risk of prostate cancer. Here, the authors show that periprostatic adipose tissue promotes the migration and local invasion of prostate cancer cells by secreting the chemokine, CCL7, and that this process is enhanced in the context of obesity. |
| format |
article |
| author |
Victor Laurent Adrien Guérard Catherine Mazerolles Sophie Le Gonidec Aurélie Toulet Laurence Nieto Falek Zaidi Bilal Majed David Garandeau Youri Socrier Muriel Golzio Thomas Cadoudal Karima Chaoui Cedric Dray Bernard Monsarrat Odile Schiltz Yuan Yuan Wang Bettina Couderc Philippe Valet Bernard Malavaud Catherine Muller |
| author_facet |
Victor Laurent Adrien Guérard Catherine Mazerolles Sophie Le Gonidec Aurélie Toulet Laurence Nieto Falek Zaidi Bilal Majed David Garandeau Youri Socrier Muriel Golzio Thomas Cadoudal Karima Chaoui Cedric Dray Bernard Monsarrat Odile Schiltz Yuan Yuan Wang Bettina Couderc Philippe Valet Bernard Malavaud Catherine Muller |
| author_sort |
Victor Laurent |
| title |
Periprostatic adipocytes act as a driving force for prostate cancer progression in obesity |
| title_short |
Periprostatic adipocytes act as a driving force for prostate cancer progression in obesity |
| title_full |
Periprostatic adipocytes act as a driving force for prostate cancer progression in obesity |
| title_fullStr |
Periprostatic adipocytes act as a driving force for prostate cancer progression in obesity |
| title_full_unstemmed |
Periprostatic adipocytes act as a driving force for prostate cancer progression in obesity |
| title_sort |
periprostatic adipocytes act as a driving force for prostate cancer progression in obesity |
| publisher |
Nature Portfolio |
| publishDate |
2016 |
| url |
https://doaj.org/article/76341f57a9a14a39a266074f59420b55 |
| work_keys_str_mv |
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| _version_ |
1718386725968936960 |