Structural and dynamic mechanisms of CBF3-guided centromeric nucleosome formation

Chromosome segregation requires the association of the kinetochore protein complex with a specialized nucleosome at the centromere. Here, the authors present cryo-EM and mutational studies that provide insights into the structure of the budding yeast centromeric nucleosome and how the centromere CBF...

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Autores principales:	Ruifang Guan, Tengfei Lian, Bing-Rui Zhou, Emily He, Carl Wu, Martin Singleton, Yawen Bai
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/763685637eb344f2b203a00440b62909
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spelling	oai:doaj.org-article:763685637eb344f2b203a00440b629092021-12-02T13:17:39ZStructural and dynamic mechanisms of CBF3-guided centromeric nucleosome formation10.1038/s41467-021-21985-92041-1723https://doaj.org/article/763685637eb344f2b203a00440b629092021-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21985-9https://doaj.org/toc/2041-1723Chromosome segregation requires the association of the kinetochore protein complex with a specialized nucleosome at the centromere. Here, the authors present cryo-EM and mutational studies that provide insights into the structure of the budding yeast centromeric nucleosome and how the centromere CBF3 protein complex guides its formation.Ruifang GuanTengfei LianBing-Rui ZhouEmily HeCarl WuMartin SingletonYawen BaiNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Ruifang Guan Tengfei Lian Bing-Rui Zhou Emily He Carl Wu Martin Singleton Yawen Bai Structural and dynamic mechanisms of CBF3-guided centromeric nucleosome formation
description	Chromosome segregation requires the association of the kinetochore protein complex with a specialized nucleosome at the centromere. Here, the authors present cryo-EM and mutational studies that provide insights into the structure of the budding yeast centromeric nucleosome and how the centromere CBF3 protein complex guides its formation.
format	article
author	Ruifang Guan Tengfei Lian Bing-Rui Zhou Emily He Carl Wu Martin Singleton Yawen Bai
author_facet	Ruifang Guan Tengfei Lian Bing-Rui Zhou Emily He Carl Wu Martin Singleton Yawen Bai
author_sort	Ruifang Guan
title	Structural and dynamic mechanisms of CBF3-guided centromeric nucleosome formation
title_short	Structural and dynamic mechanisms of CBF3-guided centromeric nucleosome formation
title_full	Structural and dynamic mechanisms of CBF3-guided centromeric nucleosome formation
title_fullStr	Structural and dynamic mechanisms of CBF3-guided centromeric nucleosome formation
title_full_unstemmed	Structural and dynamic mechanisms of CBF3-guided centromeric nucleosome formation
title_sort	structural and dynamic mechanisms of cbf3-guided centromeric nucleosome formation
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/763685637eb344f2b203a00440b62909
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Structural and dynamic mechanisms of CBF3-guided centromeric nucleosome formation

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