Structural basis of Cullin 2 RING E3 ligase regulation by the COP9 signalosome

Structural basis of Cullin 2 RING E3 ligase regulation by the COP9 signalosome

The COP9 signalosome (CSN) regulates Cullin-RING Ligase 2 (CRL2) but the molecular basis for their interaction is unknown. Here the authors use structural mass spectrometry and cryo-EM approaches to assess the structures and dynamics of CSN-CRL2 complexes.

Guardado en:
Detalles Bibliográficos
Autores principales: Sarah V. Faull, Andy M. C. Lau, Chloe Martens, Zainab Ahdash, Kjetil Hansen, Hugo Yebenes, Carla Schmidt, Fabienne Beuron, Nora B. Cronin, Edward P. Morris, Argyris Politis
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/763dbdaeaef24615aa8b9632161a84b5
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares

Ejemplares similares