Isolation and characterisation of a recombinant antibody fragment that binds NCAM1-expressing intervertebral disc cells.

Degeneration of the intervertebral discs (IVD) is a leading cause of neck and low back pain. Degeneration begins in the central nucleus pulposus region, leading to loss of IVD osmotic properties. Regeneration approaches include administration of matrix-mimicking scaffolds, cells and/or therapeutic f...

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Autores principales: Claire Cunningham, Akshay Srivastava, Estelle Collin, Sibylle Grad, Mauro Alini, Abhay Pandit, J Gerard Wall
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/7649b23856784f408908e5b98f0516ca
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